A realistic phantom for brain-shift simulations

Validation of techniques that characterize and correct for brain shift for image guided surgery requires a realistic anthropomorphic phantom for use as a gold standard. The purpose of this study was to determine the characteristics of a deformable brain phantom made of polyvinyl alcohol cryogel (PVA...

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Bibliographic Details
Published in:Medical physics (Lancaster) 2006-09, Vol.33 (9), p.3234-3240
Main Authors: Reinertsen, I., Collins, D. L.
Format: Article
Language:English
Subjects:
biomechanics
biomedical MRI
biomedical ultrasonics
Blood Proteins
blood vessels
brain
Brain - anatomy & histology
Brain - physiology
catheters
Cryogels
Doppler effect
Echoencephalography - methods
elastic deformation
Equipment Design
Equipment Failure Analysis
Fibronectins
Gels
Humans
Hydrogels
Liquid surfaces
Magnetic resonance imaging
Magnetic Resonance Imaging - instrumentation
Mechanical and electrical properties of tissues and organs
Medical diagnosis with acoustics
Medical imaging
Medical magnetic resonance imaging
Movement
phantoms
Phantoms, Imaging
Polyvinyl Alcohol
Surface measurements
surgery
Testing procedures
Tissues
Tomography, X-Ray Computed - instrumentation
Ultrasonography
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Summary:Validation of techniques that characterize and correct for brain shift for image guided surgery requires a realistic anthropomorphic phantom for use as a gold standard. The purpose of this study was to determine the characteristics of a deformable brain phantom made of polyvinyl alcohol cryogel (PVAc). The phantom was made of three layers of PVAc with inserted plastic tubes to simulate blood vessels. A catheter with an inflatable balloon was placed under the phantom in order to deform it in a nonlinear manner. The reproducibility of the elastic deformation was evaluated using MR imaging and surface measurements. Our experiments show that the phantom is well suited for MR and ultrasound imaging (B-mode and Doppler) with sub-millimeter reproducibility for the deformations.
ISSN:0094-2405
2473-4209
DOI:10.1118/1.2219091