Contrast enhanced sonography of the gallbladder: A tool in the diagnosis of cholecystitis?

Abstract Rationale and objectives To evaluate if contrast enhanced sonography (CES) can help to detect gallbladder inflammation and differentiate between acute and chronic cholecystitis. Materials and methods Thirty-three patients with clinical suspicion of acute cholecystitis were examined with CES...

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Bibliographic Details
Published in:European journal of radiology 2007-02, Vol.61 (2), p.262-266
Main Authors: Adamietz, Boris, Wenkel, Evelyn, Uder, Michael, Meyer, Thomas, Schneider, Ignaz, Dimmler, Arno, Bautz, Werner, Janka, Rolf
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cholecystitis
Cholecystitis - diagnostic imaging
Cholecystitis - pathology
Chronic Disease
Contrast Media
Female
Gallbladder - diagnostic imaging
Gallbladder - pathology
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Other diseases. Semiology
Radiology
Ultrasonography
Ultrasonography - methods
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Summary:Abstract Rationale and objectives To evaluate if contrast enhanced sonography (CES) can help to detect gallbladder inflammation and differentiate between acute and chronic cholecystitis. Materials and methods Thirty-three patients with clinical suspicion of acute cholecystitis were examined with CES before cholecystectomy. Thirty patients with no history of gallbladder disease served as control. CES was performed using 2.5 mL SonoVue. A small mechanical index was chosen (0.1). The enhancement pattern of the gallbladder was ranked in a three-point scale: no enhancement, low enhancement and strong enhancement. 28/33 patients underwent surgery. Sonographic findings were compared to histological results. Results In 16/20 cases with histological proven acute cholecystitis, the gallbladder wall showed a strong enhancement. Low enhancement was found in four patients with acute and in six patients with chronic cholecystitis. The gallbladder wall of two patients with chronic inflammation and all patients (30/30) of the control group showed no enhancement. Conclusion CES is a feasible tool for detecting gallbladder inflammation. Differentiating between acute and chronic cholecystitis seems to be possible.
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2006.09.006