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Ruthenium-Catalyzed Tandem Olefin Metathesis−Oxidations

The utility of Grubbs' 2nd generation metathesis catalyst has been expanded by the development of two tandem olefin metathesis/oxidation protocols. These ruthenium-catalyzed processes provide cis-diols or α-hydroxy ketones from simple olefinic starting materials.

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Bibliographic Details
Published in:Organic letters 2006-10, Vol.8 (21), p.4759-4762
Main Authors: Scholte, Andrew A, An, Mi Hyun, Snapper, Marc L
Format: Article
Language:English
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Description
Summary:The utility of Grubbs' 2nd generation metathesis catalyst has been expanded by the development of two tandem olefin metathesis/oxidation protocols. These ruthenium-catalyzed processes provide cis-diols or α-hydroxy ketones from simple olefinic starting materials.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol061837n