Loading…

Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects

Background Progression of aortic regurgitation (AR) in repaired outlet ventricular septal defects (VSDs) remains unclear, especially for muscular outlet and perimembranous outlet VSDs. We tried to identify the risk factors for AR progression and aortic valve replacement (AVR) at long-term follow-up....

Full description

Saved in:
Bibliographic Details
Published in:The American heart journal 2007-02, Vol.153 (2), p.336-342
Main Authors: Chiu, Shuenn-Nan, MD, Wang, Jou-Kou, MD, PhD, Lin, Ming-Tai, MD, Chen, Chun-An, MD, Chen, Hui-Chi, BS, MS, Chang, Chung-I, MD, Chen, Yih-Sharng, MD, PhD, Chiu, Ing-Sh, MD, PhD, Lue, Hung-Chi, MD, Wu, Mei-Hwan, MD, PhD
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463
cites cdi_FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463
container_end_page 342
container_issue 2
container_start_page 336
container_title The American heart journal
container_volume 153
creator Chiu, Shuenn-Nan, MD
Wang, Jou-Kou, MD, PhD
Lin, Ming-Tai, MD
Chen, Chun-An, MD
Chen, Hui-Chi, BS, MS
Chang, Chung-I, MD
Chen, Yih-Sharng, MD, PhD
Chiu, Ing-Sh, MD, PhD
Lue, Hung-Chi, MD
Wu, Mei-Hwan, MD, PhD
description Background Progression of aortic regurgitation (AR) in repaired outlet ventricular septal defects (VSDs) remains unclear, especially for muscular outlet and perimembranous outlet VSDs. We tried to identify the risk factors for AR progression and aortic valve replacement (AVR) at long-term follow-up. Methods Four hundred patients with complete follow-up after the repair of their outlet VSD between 1987 and 2002 were studied. Results Juxta-arterial VSD, perimembranous outlet VSD, and muscular outlet VSD were noted in 190, 148, and 62 patients, respectively. There were 377 patients with none to mild AR (group I) and 23 with moderate to severe AR (group II) preoperatively. Aortic valve replacement was performed on 11 patients (all from group II), with 10 having received AVR concomitantly with VSD repair and 1 having received it 4 years later. Only severity of preoperative AR and older age (>15 years) at VSD repair were significant predictors of AVR. With a total follow-up of 2230 person-years, the 10-year freedom from AVR after VSD repair for group I was 100% and that for group II was 50.2%. In group I, AR progressed in 4 patients only (1.2%, 2 juxta-arterial and 2 perimembranous outlet) and aortic valvular (aortic valve prolapse or ruptured sinus Valsalva aneurysm) or subvalvular anomalies were present in all. The event-free (AR or AVR) survival rates among the 3 outlet-type VSDs however showed no difference. Conclusions Aortic regurgitation progression modes after surgical VSD repair were similar among the 3 outlet-type VSDs. Aortic valve replacement was rarely necessary for patients who were operated on when they were younger than 15 years. Aortic regurgitation of a less-than-moderate degree preoperatively rarely progressed after VSD repair.
doi_str_mv 10.1016/j.ahj.2006.10.025
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68935029</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002870306009525</els_id><sourcerecordid>68935029</sourcerecordid><originalsourceid>FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463</originalsourceid><addsrcrecordid>eNp9kl-L1DAUxYMo7rj6AXyRguhbx5s0TRuEBVn8BwsK6nNI05sxtdOMSbow396EGRjYB5_Cvfndw8nJJeQlhS0FKt5NW_172jIAkestsPYR2VCQXS06zh-TDQCwuu-guSLPYpxyKVgvnpIr2rFGCik3xHwPfhcwRueXyttK-5CcqQLu1rBzSafS1zZhqGLpGD3ny4N2odB-TTOmOh0PWN3jkoIz66wzioeUwREtmhSfkydWzxFfnM9r8uvTx5-3X-q7b5-_3n64q03bQMqmwWRf2NjBDHxglhnet6aRw8B03-PIrGlQyr5BxviAduDAKUUOvdaUi-aavD3pHoL_u2JMau-iwXnWC_o1KtHLpgUmM_j6ATj5NSzZm6ItcAFStEWOnigTfIwBrToEt9fhqCiokr-aVM5flfxLK-efZ16dlddhj-Nl4hx4Bt6cAR1zljboxbh44aQEIbs-c-9PHObA7h0GFY3DxeDoQs5Ujd7918bNg2kzu6V83h88Yry8VkWmQP0oi1L2BASAbLPAPw9QuK4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1504609656</pqid></control><display><type>article</type><title>Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects</title><source>ScienceDirect Freedom Collection</source><creator>Chiu, Shuenn-Nan, MD ; Wang, Jou-Kou, MD, PhD ; Lin, Ming-Tai, MD ; Chen, Chun-An, MD ; Chen, Hui-Chi, BS, MS ; Chang, Chung-I, MD ; Chen, Yih-Sharng, MD, PhD ; Chiu, Ing-Sh, MD, PhD ; Lue, Hung-Chi, MD ; Wu, Mei-Hwan, MD, PhD</creator><creatorcontrib>Chiu, Shuenn-Nan, MD ; Wang, Jou-Kou, MD, PhD ; Lin, Ming-Tai, MD ; Chen, Chun-An, MD ; Chen, Hui-Chi, BS, MS ; Chang, Chung-I, MD ; Chen, Yih-Sharng, MD, PhD ; Chiu, Ing-Sh, MD, PhD ; Lue, Hung-Chi, MD ; Wu, Mei-Hwan, MD, PhD</creatorcontrib><description>Background Progression of aortic regurgitation (AR) in repaired outlet ventricular septal defects (VSDs) remains unclear, especially for muscular outlet and perimembranous outlet VSDs. We tried to identify the risk factors for AR progression and aortic valve replacement (AVR) at long-term follow-up. Methods Four hundred patients with complete follow-up after the repair of their outlet VSD between 1987 and 2002 were studied. Results Juxta-arterial VSD, perimembranous outlet VSD, and muscular outlet VSD were noted in 190, 148, and 62 patients, respectively. There were 377 patients with none to mild AR (group I) and 23 with moderate to severe AR (group II) preoperatively. Aortic valve replacement was performed on 11 patients (all from group II), with 10 having received AVR concomitantly with VSD repair and 1 having received it 4 years later. Only severity of preoperative AR and older age (&gt;15 years) at VSD repair were significant predictors of AVR. With a total follow-up of 2230 person-years, the 10-year freedom from AVR after VSD repair for group I was 100% and that for group II was 50.2%. In group I, AR progressed in 4 patients only (1.2%, 2 juxta-arterial and 2 perimembranous outlet) and aortic valvular (aortic valve prolapse or ruptured sinus Valsalva aneurysm) or subvalvular anomalies were present in all. The event-free (AR or AVR) survival rates among the 3 outlet-type VSDs however showed no difference. Conclusions Aortic regurgitation progression modes after surgical VSD repair were similar among the 3 outlet-type VSDs. Aortic valve replacement was rarely necessary for patients who were operated on when they were younger than 15 years. Aortic regurgitation of a less-than-moderate degree preoperatively rarely progressed after VSD repair.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/j.ahj.2006.10.025</identifier><identifier>PMID: 17239699</identifier><identifier>CODEN: AHJOA2</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adolescent ; Adult ; Age ; Aortic Valve Insufficiency - epidemiology ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Child ; Child, Preschool ; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava ; Defects ; Disease Progression ; Endocardial and cardiac valvular diseases ; Female ; Follow-Up Studies ; Heart ; Heart Septal Defects, Ventricular - pathology ; Heart Septal Defects, Ventricular - surgery ; Humans ; Infant ; Infant, Newborn ; Intubation ; Male ; Medical imaging ; Medical sciences ; Middle Aged ; Mortality ; Pulmonary arteries ; Risk Factors ; Sinuses ; Surgery ; Time Factors ; Veins &amp; arteries</subject><ispartof>The American heart journal, 2007-02, Vol.153 (2), p.336-342</ispartof><rights>Mosby, Inc.</rights><rights>2007 Mosby, Inc.</rights><rights>2008 INIST-CNRS</rights><rights>Copyright Elsevier Limited Feb 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463</citedby><cites>FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=19906978$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17239699$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chiu, Shuenn-Nan, MD</creatorcontrib><creatorcontrib>Wang, Jou-Kou, MD, PhD</creatorcontrib><creatorcontrib>Lin, Ming-Tai, MD</creatorcontrib><creatorcontrib>Chen, Chun-An, MD</creatorcontrib><creatorcontrib>Chen, Hui-Chi, BS, MS</creatorcontrib><creatorcontrib>Chang, Chung-I, MD</creatorcontrib><creatorcontrib>Chen, Yih-Sharng, MD, PhD</creatorcontrib><creatorcontrib>Chiu, Ing-Sh, MD, PhD</creatorcontrib><creatorcontrib>Lue, Hung-Chi, MD</creatorcontrib><creatorcontrib>Wu, Mei-Hwan, MD, PhD</creatorcontrib><title>Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>Background Progression of aortic regurgitation (AR) in repaired outlet ventricular septal defects (VSDs) remains unclear, especially for muscular outlet and perimembranous outlet VSDs. We tried to identify the risk factors for AR progression and aortic valve replacement (AVR) at long-term follow-up. Methods Four hundred patients with complete follow-up after the repair of their outlet VSD between 1987 and 2002 were studied. Results Juxta-arterial VSD, perimembranous outlet VSD, and muscular outlet VSD were noted in 190, 148, and 62 patients, respectively. There were 377 patients with none to mild AR (group I) and 23 with moderate to severe AR (group II) preoperatively. Aortic valve replacement was performed on 11 patients (all from group II), with 10 having received AVR concomitantly with VSD repair and 1 having received it 4 years later. Only severity of preoperative AR and older age (&gt;15 years) at VSD repair were significant predictors of AVR. With a total follow-up of 2230 person-years, the 10-year freedom from AVR after VSD repair for group I was 100% and that for group II was 50.2%. In group I, AR progressed in 4 patients only (1.2%, 2 juxta-arterial and 2 perimembranous outlet) and aortic valvular (aortic valve prolapse or ruptured sinus Valsalva aneurysm) or subvalvular anomalies were present in all. The event-free (AR or AVR) survival rates among the 3 outlet-type VSDs however showed no difference. Conclusions Aortic regurgitation progression modes after surgical VSD repair were similar among the 3 outlet-type VSDs. Aortic valve replacement was rarely necessary for patients who were operated on when they were younger than 15 years. Aortic regurgitation of a less-than-moderate degree preoperatively rarely progressed after VSD repair.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aortic Valve Insufficiency - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</subject><subject>Defects</subject><subject>Disease Progression</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Heart Septal Defects, Ventricular - pathology</subject><subject>Heart Septal Defects, Ventricular - surgery</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Intubation</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Pulmonary arteries</subject><subject>Risk Factors</subject><subject>Sinuses</subject><subject>Surgery</subject><subject>Time Factors</subject><subject>Veins &amp; arteries</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNp9kl-L1DAUxYMo7rj6AXyRguhbx5s0TRuEBVn8BwsK6nNI05sxtdOMSbow396EGRjYB5_Cvfndw8nJJeQlhS0FKt5NW_172jIAkestsPYR2VCQXS06zh-TDQCwuu-guSLPYpxyKVgvnpIr2rFGCik3xHwPfhcwRueXyttK-5CcqQLu1rBzSafS1zZhqGLpGD3ny4N2odB-TTOmOh0PWN3jkoIz66wzioeUwREtmhSfkydWzxFfnM9r8uvTx5-3X-q7b5-_3n64q03bQMqmwWRf2NjBDHxglhnet6aRw8B03-PIrGlQyr5BxviAduDAKUUOvdaUi-aavD3pHoL_u2JMau-iwXnWC_o1KtHLpgUmM_j6ATj5NSzZm6ItcAFStEWOnigTfIwBrToEt9fhqCiokr-aVM5flfxLK-efZ16dlddhj-Nl4hx4Bt6cAR1zljboxbh44aQEIbs-c-9PHObA7h0GFY3DxeDoQs5Ujd7918bNg2kzu6V83h88Yry8VkWmQP0oi1L2BASAbLPAPw9QuK4</recordid><startdate>20070201</startdate><enddate>20070201</enddate><creator>Chiu, Shuenn-Nan, MD</creator><creator>Wang, Jou-Kou, MD, PhD</creator><creator>Lin, Ming-Tai, MD</creator><creator>Chen, Chun-An, MD</creator><creator>Chen, Hui-Chi, BS, MS</creator><creator>Chang, Chung-I, MD</creator><creator>Chen, Yih-Sharng, MD, PhD</creator><creator>Chiu, Ing-Sh, MD, PhD</creator><creator>Lue, Hung-Chi, MD</creator><creator>Wu, Mei-Hwan, MD, PhD</creator><general>Mosby, Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20070201</creationdate><title>Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects</title><author>Chiu, Shuenn-Nan, MD ; Wang, Jou-Kou, MD, PhD ; Lin, Ming-Tai, MD ; Chen, Chun-An, MD ; Chen, Hui-Chi, BS, MS ; Chang, Chung-I, MD ; Chen, Yih-Sharng, MD, PhD ; Chiu, Ing-Sh, MD, PhD ; Lue, Hung-Chi, MD ; Wu, Mei-Hwan, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Aortic Valve Insufficiency - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava</topic><topic>Defects</topic><topic>Disease Progression</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart</topic><topic>Heart Septal Defects, Ventricular - pathology</topic><topic>Heart Septal Defects, Ventricular - surgery</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Intubation</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Pulmonary arteries</topic><topic>Risk Factors</topic><topic>Sinuses</topic><topic>Surgery</topic><topic>Time Factors</topic><topic>Veins &amp; arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chiu, Shuenn-Nan, MD</creatorcontrib><creatorcontrib>Wang, Jou-Kou, MD, PhD</creatorcontrib><creatorcontrib>Lin, Ming-Tai, MD</creatorcontrib><creatorcontrib>Chen, Chun-An, MD</creatorcontrib><creatorcontrib>Chen, Hui-Chi, BS, MS</creatorcontrib><creatorcontrib>Chang, Chung-I, MD</creatorcontrib><creatorcontrib>Chen, Yih-Sharng, MD, PhD</creatorcontrib><creatorcontrib>Chiu, Ing-Sh, MD, PhD</creatorcontrib><creatorcontrib>Lue, Hung-Chi, MD</creatorcontrib><creatorcontrib>Wu, Mei-Hwan, MD, PhD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Health Management Database (ProQuest)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest research library</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chiu, Shuenn-Nan, MD</au><au>Wang, Jou-Kou, MD, PhD</au><au>Lin, Ming-Tai, MD</au><au>Chen, Chun-An, MD</au><au>Chen, Hui-Chi, BS, MS</au><au>Chang, Chung-I, MD</au><au>Chen, Yih-Sharng, MD, PhD</au><au>Chiu, Ing-Sh, MD, PhD</au><au>Lue, Hung-Chi, MD</au><au>Wu, Mei-Hwan, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>2007-02-01</date><risdate>2007</risdate><volume>153</volume><issue>2</issue><spage>336</spage><epage>342</epage><pages>336-342</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><coden>AHJOA2</coden><abstract>Background Progression of aortic regurgitation (AR) in repaired outlet ventricular septal defects (VSDs) remains unclear, especially for muscular outlet and perimembranous outlet VSDs. We tried to identify the risk factors for AR progression and aortic valve replacement (AVR) at long-term follow-up. Methods Four hundred patients with complete follow-up after the repair of their outlet VSD between 1987 and 2002 were studied. Results Juxta-arterial VSD, perimembranous outlet VSD, and muscular outlet VSD were noted in 190, 148, and 62 patients, respectively. There were 377 patients with none to mild AR (group I) and 23 with moderate to severe AR (group II) preoperatively. Aortic valve replacement was performed on 11 patients (all from group II), with 10 having received AVR concomitantly with VSD repair and 1 having received it 4 years later. Only severity of preoperative AR and older age (&gt;15 years) at VSD repair were significant predictors of AVR. With a total follow-up of 2230 person-years, the 10-year freedom from AVR after VSD repair for group I was 100% and that for group II was 50.2%. In group I, AR progressed in 4 patients only (1.2%, 2 juxta-arterial and 2 perimembranous outlet) and aortic valvular (aortic valve prolapse or ruptured sinus Valsalva aneurysm) or subvalvular anomalies were present in all. The event-free (AR or AVR) survival rates among the 3 outlet-type VSDs however showed no difference. Conclusions Aortic regurgitation progression modes after surgical VSD repair were similar among the 3 outlet-type VSDs. Aortic valve replacement was rarely necessary for patients who were operated on when they were younger than 15 years. Aortic regurgitation of a less-than-moderate degree preoperatively rarely progressed after VSD repair.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>17239699</pmid><doi>10.1016/j.ahj.2006.10.025</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0002-8703
ispartof The American heart journal, 2007-02, Vol.153 (2), p.336-342
issn 0002-8703
1097-6744
language eng
recordid cdi_proquest_miscellaneous_68935029
source ScienceDirect Freedom Collection
subjects Adolescent
Adult
Age
Aortic Valve Insufficiency - epidemiology
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular
Child
Child, Preschool
Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
Defects
Disease Progression
Endocardial and cardiac valvular diseases
Female
Follow-Up Studies
Heart
Heart Septal Defects, Ventricular - pathology
Heart Septal Defects, Ventricular - surgery
Humans
Infant
Infant, Newborn
Intubation
Male
Medical imaging
Medical sciences
Middle Aged
Mortality
Pulmonary arteries
Risk Factors
Sinuses
Surgery
Time Factors
Veins & arteries
title Progression of aortic regurgitation after surgical repair of outlet-type ventricular septal defects
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T10%3A00%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Progression%20of%20aortic%20regurgitation%20after%20surgical%20repair%20of%20outlet-type%20ventricular%20septal%20defects&rft.jtitle=The%20American%20heart%20journal&rft.au=Chiu,%20Shuenn-Nan,%20MD&rft.date=2007-02-01&rft.volume=153&rft.issue=2&rft.spage=336&rft.epage=342&rft.pages=336-342&rft.issn=0002-8703&rft.eissn=1097-6744&rft.coden=AHJOA2&rft_id=info:doi/10.1016/j.ahj.2006.10.025&rft_dat=%3Cproquest_cross%3E68935029%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c530t-670c723e3fbcb4b2f2c485c39bb2a88ed2fc3e9983e224befb40411e408aa1463%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1504609656&rft_id=info:pmid/17239699&rfr_iscdi=true