Complications and other surgical outcomes associated with extended pelvic lymphadenectomy in men with localized prostate cancer

More-extensive pelvic lymph node dissection (PLND) may be associated with a higher rate of complications and a longer hospital stay than more limited PLND. Before radical retropubic prostatectomy, PLNDs were performed in 963 patients. Of these, 767 (79.6%) had >or=10 lymph nodes removed and exami...

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Published in:European urology 2006-11, Vol.50 (5), p.1006-1013
Main Authors: BRIGANTI, Alberto, CHUN, Felix K.-H, MONTORSI, Francesco, KARAKIEWICZ, Pierre I, SALONIA, Andrea, SUARDI, Nazareno, GALLINA, Andrea, DA POZZO, Luigi Filippo, ROSCIGNO, Marco, ZANNI, Giuseppe, VALIQUETTE, Luc, RIGATTI, Patrizio
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Gynecology. Andrology. Obstetrics
Humans
Lymph Node Excision - methods
Male
Male genital diseases
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Pelvis - surgery
Postoperative Complications
Prostatic Neoplasms - pathology
ROC Curve
Tumors
Tumors of the urinary system
Urinary tract. Prostate gland
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Summary:More-extensive pelvic lymph node dissection (PLND) may be associated with a higher rate of complications and a longer hospital stay than more limited PLND. Before radical retropubic prostatectomy, PLNDs were performed in 963 patients. Of these, 767 (79.6%) had >or=10 lymph nodes removed and examined (extended PLND [ePLND]), while 1-9 nodes (limited PLND [lPLND]) were removed in the remaining 196 (20.4%). Limits included external iliac, obturator, internal iliac, and iliac bifurcation. PLND-related complications and the length of hospital stay were recorded prospectively and analyzed according to the extent of PLND. In patients subjected to ePLND, the overall rate of complications was 19.8% versus 8.2% in those treated with lPLND (p
ISSN:0302-2838
1873-7560
DOI:10.1016/j.eururo.2006.08.015