Sonohysterography versus transvaginal sonography for screening of patients with abnormal uterine bleeding

• Published in: International journal of gynecology and obstetrics 2007-01, Vol.96 (1), p.20-23
• Main Authors: Alborzi, S., Parsanezhad, M.E., Mahmoodian, N., Alborzi, M.
• Format: Article
• Language: English
• Subjects: Abnormal uterine bleeding (AUB); Adenomyosis; Biological and medical sciences; Endometriosis - diagnostic imaging; Endosonography - methods; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Humans; Leiomyoma - diagnostic imaging; Medical sciences; Metrorrhagia - diagnostic imaging; Myoma; Non tumoral diseases; Obstetrics and Gynecology; Polyp; Saline infusion sonohysterography (SIS); Sensitivity and Specificity; Sodium Chloride - administration & dosage; Transvaginal sonography (TVS); Uterine Neoplasms - diagnostic imaging; Uterus - diagnostic imaging
• ISSN: 0020-7292; 1879-3479
• DOI: 10.1016/j.ijgo.2006.09.004

Abstract Objectives To compare the accuracy of saline infusion sonohysterography (SIS) with transvaginal sonography (TVS) for the screening of causes of abnormal uterine bleeding (AUB) in out-patients. Methods 81 patients with AUB were studied. All cases who were examined with TVS, were further investigated with SIS using saline as contrast medium, finally hysteroscopy was used as the gold standard. Results TVS had sensitivity of 72%, specificity of 92%, positive predictive value of 94% and negative predictive value of 65%, while SIS had sensitivity of 94.1%, specificity of 95%, positive predictive value of 96% and negative predictive value of 90%. TVS had kappa measure of agreement of 0.60 while 0.86 was reported for SIS. Conclusions In this study SIS was more sensitive and specific in diagnosing polyp, myoma and adenomyosis with high positive and negative predictive value. Furthermore, results obtained by SIS demonstrate more agreement with that obtained by hysteroscopy than TVS.