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Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease

Our study investigates nutritional status, resting energy expenditure (REE) and physical performance in elderly patients with stable COPD to identify any early conditions of hypermetabolism, malnutrition and sarcopenia. Eighty-six males (40 stable COPD and 46 healthy subjects) over 65 years old were...

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Bibliographic Details
Published in:Respiratory medicine 2006-11, Vol.100 (11), p.1918-1924
Main Authors: Sergi, Giuseppe, Coin, Alessandra, Marin, Sara, Vianello, Andrea, Manzan, Alessandro, Peruzza, Silvia, Inelmen, Emine Meral, Busetto, Luca, Mulone, Silvana, Enzi, Giuliano
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Language:English
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Summary:Our study investigates nutritional status, resting energy expenditure (REE) and physical performance in elderly patients with stable COPD to identify any early conditions of hypermetabolism, malnutrition and sarcopenia. Eighty-six males (40 stable COPD and 46 healthy subjects) over 65 years old were studied. All subjects underwent spirometry, blood gas analysis and a 6-min walking test (6MWT). Fat-free mass (FFM) and appendicular skeletal muscle mass (ASMM) were measured by dual energy X-ray absorptiometry (DEXA). REE was measured by indirect calorimetry. COPD patients had a lower FFM both expressed in kilograms and after correction for height squared. The prevalence of sarcopenia was higher for COPD subjects (38% vs 31%). REE, both in absolute values and adjusted for FFM was significantly higher in COPD patients. Hypermetabolism was found in 60% of COPD cases and 13.7% ( P
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2006.03.008