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Indican interference in bilirubin assays: a classical solution still applies

To test the effect of indican, we added indican (indoxyl sulfate; Sigma-Aldrich) to a plasma pool generated from patients with normal renal function. The time course of absorbance for the new Abbott bilirubin assay matches that seen during analysis of plasma from dialysis patients.

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Bibliographic Details
Published in:Clinical chemistry (Baltimore, Md.) Md.), 2007-02, Vol.53 (2), p.359-361
Main Authors: Henrich, Lorin M, Bruns, David E, Haverstick, Doris M, Reynolds, Victoria G, Boyd, James C
Format: Article
Language:English
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Description
Summary:To test the effect of indican, we added indican (indoxyl sulfate; Sigma-Aldrich) to a plasma pool generated from patients with normal renal function. The time course of absorbance for the new Abbott bilirubin assay matches that seen during analysis of plasma from dialysis patients.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2006.083154