Association of Atrial Fibrillation in Patients With Interatrial Block Over Prospectively Followed Controls With Comparable Echocardiographic Parameters

Interatrial block (IAB) (P wave ≥110 ms) is a potential risk of atrial fibrillation (AF). However, few investigations have assessed the relevance of echocardiographic parameters, particularly the contribution of its known correlate, left atrial enlargement in this regard. We identified 32 consecutiv...

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Bibliographic Details
Published in:The American journal of cardiology 2007-02, Vol.99 (3), p.390-392
Main Authors: Ariyarajah, Vignendra, MD, Apiyasawat, Sirin, MD, Fernandes, Jaxon, MD, Kranis, Mark, DO, Spodick, David H., MD, DSc
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Atrial Fibrillation - diagnostic imaging
Atrial Fibrillation - epidemiology
Atrial Fibrillation - etiology
Biological and medical sciences
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology. Vascular system
Cardiovascular
Cardiovascular system
Disease Progression
Echocardiography - methods
Electrocardiography
Female
Follow-Up Studies
Heart
Heart Rate - physiology
Humans
Incidence
Investigative techniques, diagnostic techniques (general aspects)
Male
Massachusetts - epidemiology
Medical sciences
Prevalence
Prognosis
Prospective Studies
Risk Factors
Sinoatrial Block - complications
Sinoatrial Block - diagnostic imaging
Sinoatrial Block - physiopathology
Stroke Volume - physiology
Ultrasonic imaging
Ultrasonic investigative techniques
Ventricular Function, Left - physiology
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Summary:Interatrial block (IAB) (P wave ≥110 ms) is a potential risk of atrial fibrillation (AF). However, few investigations have assessed the relevance of echocardiographic parameters, particularly the contribution of its known correlate, left atrial enlargement in this regard. We identified 32 consecutive patients with comparable echocardiographic parameters, such as left atrial dimension and left ventricular ejection fraction. Patients were evaluated for IAB and followed for 15 months for cardiovascular events (heart failure, transient ischemic attacks, and stroke), atrial tachyarrhythmias (AF/atrial flutter), and death. Preexisting AF and IAB (p = 0.02) were significantly associated with future AF events. However, logistic regression analysis indicated that IAB was not an independent predictor of future AF, only preexisting atrial tachyarrhythmias was (hazard ratio 39.5, 95% confidence interval 2.7 to 576.3, p = 0.007). In conclusion, in patients with comparable echocardiographic parameters, such as left atrial size and left ventricular ejection fraction, IAB remained associated with AF after a 15-month follow-up. Additional investigation is needed to confirm the extent of the association.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2006.08.043