Pathological diagnosis of granulomatous lung disease: a review

Granulomas in the lung are common diagnostic problems encountered by pathologists. They occur in a wide range of pulmonary conditions, ranging from common entities to uncommon ones and including both infections and non‐infectious diseases. This review summarizes the main histological features that h...

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Bibliographic Details
Published in:Histopathology 2007-02, Vol.50 (3), p.289-310
Main Authors: El-Zammar, O A, Katzenstein, A-L A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Diagnosis, Differential
Granuloma, Respiratory Tract - microbiology
Granuloma, Respiratory Tract - pathology
Granulomatosis with Polyangiitis - diagnosis
granulomatous lung disease
Humans
Investigative techniques, diagnostic techniques (general aspects)
Lung Diseases - classification
Lung Diseases - pathology
lung granuloma
Medical sciences
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
sarcoidosis
Sarcoidosis - diagnosis
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
tuberculosis
Tuberculosis, Pulmonary - diagnosis
Wegener's granulomatosis
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Summary:Granulomas in the lung are common diagnostic problems encountered by pathologists. They occur in a wide range of pulmonary conditions, ranging from common entities to uncommon ones and including both infections and non‐infectious diseases. This review summarizes the main histological features that help distinguish various granulomatous lung diseases. It concentrates on the most important and common entities that may be encountered and emphasizes helpful features in the differential diagnosis.
ISSN:0309-0167
1365-2559
DOI:10.1111/j.1365-2559.2006.02546.x