Intra-arterial thrombolytic therapy for acute basilar occlusion : Pro

Acute thromboembolic occlusion of the basilar artery accounts for 6% to 10% of large-vessel stroke in humans. Because of the brain region supplied by this artery, the case fatality rate is the highest for all ischemic stroke subtypes, ranging from 40% to 86%. Patients who undergo successful recanali...

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Bibliographic Details
Published in:Stroke (1970) 2007-02, Vol.38 (2), p.701-703
Main Author: SMITH, Wade S
Format: Article
Language:English
Subjects:
Animals
Anti-Arrhythmia Agents - administration & dosage
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Drug toxicity and drugs side effects treatment
Humans
Infusions, Intra-Arterial - methods
Medical sciences
Neurology
Pharmacology. Drug treatments
Thrombolytic Therapy - methods
Toxicity: blood
Vascular diseases and vascular malformations of the nervous system
Vertebrobasilar Insufficiency - drug therapy
Vertebrobasilar Insufficiency - mortality
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Summary:Acute thromboembolic occlusion of the basilar artery accounts for 6% to 10% of large-vessel stroke in humans. Because of the brain region supplied by this artery, the case fatality rate is the highest for all ischemic stroke subtypes, ranging from 40% to 86%. Patients who undergo successful recanalization of the basilar artery by intra-arterial thrombolysis have lower mortality of approximately 39%. Considering all published series, a consistent survival benefit is predicted by revascularization (mortality 87% nonrecanalized compared with 39% recanalized; P
ISSN:0039-2499
1524-4628
DOI:10.1161/01.STR.0000247897.33267.42