Molecular recognition of oxoanions based on guanidinium receptors

Guanidinium is a versatile functional group with unique properties. In biological systems, hydrogen-bonding and electrostatic interactions involving the arginine side chains of proteins are critical to stabilise complexes between proteins and nucleic acids, carbohydrates or other proteins. Leading e...

Full description

Saved in:
Bibliographic Details
Published in:Chemical Society reviews 2007-01, Vol.36 (2), p.198-210
Main Authors: Blondeau, Pascal, Segura, Margarita, Pérez-Fernández, Ruth, de Mendoza, Javier
Format: Article
Language:English
Subjects:
Anions
Binding Sites
Carboxylic Acids - chemistry
DNA - chemistry
DNA - metabolism
Guanidine - chemistry
Models, Molecular
Proteins - chemistry
Proteins - metabolism
Receptors, Cell Surface - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Guanidinium is a versatile functional group with unique properties. In biological systems, hydrogen-bonding and electrostatic interactions involving the arginine side chains of proteins are critical to stabilise complexes between proteins and nucleic acids, carbohydrates or other proteins. Leading examples of artificial receptors for carboxylates, phosphates and other oxoanions, such as sulfate or nitrate are highlighted in this tutorial review, addressed to readers interested in biology, chemistry and supramolecular chemistry.
ISSN:0306-0012
1460-4744
DOI:10.1039/b603089k