Molecularly imprinted polymers in clinical diagnostics—Future potential and existing problems

The last five years have witnessed a fast progress in the area of molecularly imprinted polymers (MIPs). These have included the development of rational protocols for polymer design (combinatorial and computational), the development of MIPs compatible for use in aqueous environment and the developme...

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Bibliographic Details
Published in:Medical engineering & physics 2006-12, Vol.28 (10), p.971-977
Main Authors: Piletsky, Sergey A., Turner, Nicholas W., Laitenberger, Peter
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Biosensing Techniques - instrumentation
Biosensing Techniques - trends
Clinical analysis
Diagnostic Equipment - trends
Diagnostics
Forecasting
Molecular Probe Techniques - instrumentation
Molecular Probe Techniques - trends
Molecularly imprinted polymers
Polymers - chemistry
Sensors
Surface Properties
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Summary:The last five years have witnessed a fast progress in the area of molecularly imprinted polymers (MIPs). These have included the development of rational protocols for polymer design (combinatorial and computational), the development of MIPs compatible for use in aqueous environment and the development of various procedures for the integration of MIPs with sensors. The substantial improvements in the performance of imprinted polymers have also been accompanied by a growing number of MIP publications related to solving practical problems associated with their use, e.g. in environmental and clinical analysis. This paper furnishes a detailed analysis of recent achievements in MIPs design and applications related to healthcare, made by our group as well as others worldwide.
ISSN:1350-4533
1873-4030
DOI:10.1016/j.medengphy.2006.05.004