Comparison of Coronary Restenosis Rates in Matched Patients With Versus Without Diabetes Mellitus

Diabetes mellitus (DM) is an established risk factor for stent restenosis, in part as a result of the smaller vessel dimensions and longer lesions. This study compared the magnitude of acute lumen gain and late lumen loss after elective coronary stent implantation in patients with and without DM usi...

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Bibliographic Details
Published in:The American journal of cardiology 2006-11, Vol.98 (9), p.1218-1222
Main Authors: Radke, Peter W., Friese, Klara, Buhr, Andrea, Nagel, Bernard, Harland, Lars-Christian, Kaiser, Axel, Remmel, Marko, Hanrath, Peter, Schunkert, Heribert, Hoffmann, Rainer
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Biological and medical sciences
Cardiology. Vascular system
Case-Control Studies
Comparative analysis
Coronary Angiography
Coronary heart disease
Coronary Restenosis - diagnostic imaging
Coronary Restenosis - epidemiology
Coronary Restenosis - etiology
Coronary Stenosis - therapy
Diabetes
Diabetes Complications - diagnostic imaging
Diabetes Complications - epidemiology
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Follow-Up Studies
Heart
Humans
Male
Medical disorders
Medical sciences
Middle Aged
Predictive Value of Tests
Risk Factors
Stents
Treatment Outcome
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Summary:Diabetes mellitus (DM) is an established risk factor for stent restenosis, in part as a result of the smaller vessel dimensions and longer lesions. This study compared the magnitude of acute lumen gain and late lumen loss after elective coronary stent implantation in patients with and without DM using a matched-pair analysis. A total of 133 patients with DM and 192 coronary lesions were included in this analysis. A group of 192 lesions in 182 patients without DM were matched in a pairwise fashion, stratifying for reference diameter, minimal luminal diameter, and lesion length. The binary restenosis rate at the 5-month follow-up angiography was 25% in the DM group and 14% in the non-DM group (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2006.06.015