Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age

Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for a...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2006-11, Vol.98 (9), p.1238-1241
Main Authors: Jozwiak, Andrzej, Guzik, Przemyslaw, Mathew, Anup, Wykretowicz, Andrzej, Wysocki, Henryk
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Analysis of Variance
Atrial Fibrillation - complications
Atrial Fibrillation - physiopathology
Biological and medical sciences
Cardiac dysrhythmias
Cardiology. Vascular system
Cardiovascular disease
Cognition & reasoning
Cognition Disorders - etiology
Cognition Disorders - physiopathology
Female
Heart
Hospitalization
Humans
Inpatients
Male
Medical sciences
Nervous System Diseases - complications
Nervous System Diseases - etiology
Nervous System Diseases - physiopathology
Neurology
Neuropsychological Tests
Older people
Psychomotor Performance
Retrospective Studies
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483
cites cdi_FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483
container_end_page 1241
container_issue 9
container_start_page 1238
container_title The American journal of cardiology
container_volume 98
creator Jozwiak, Andrzej
Guzik, Przemyslaw
Mathew, Anup
Wykretowicz, Andrzej
Wysocki, Henryk
description Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for any reason and grouped according to the presence of AF and/or FNDs. Data on 2,314 conscious patients aged ≥65 years (1,506 women) were analyzed. Physical examination, electrocardiography at rest, and the Mini-Mental State Examination were performed at admission. The median Mini-Mental State Examination score was 25 in patients without AF or FNDs (63.4%), 23 in those with AF alone (23.6%), 21 in those with FNDs alone (8.9%), and 18 in those with AF and FNDs (4.1%). On multivariate logistic regression (adjusted for age and gender), the risk for ICF was increased in patients with AF alone (p
doi_str_mv 10.1016/j.amjcard.2006.05.058
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68980482</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002914906013750</els_id><sourcerecordid>1189808131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483</originalsourceid><addsrcrecordid>eNqFkc-KFDEQxoMo7rj6CEoQ9NZj_nU6OckwOu7Coh4U8RTS6fRYTXdnNule0Dfw4GP4Yj6JmZ2GBS9CQaji91VV6kPoKSVrSqh81a3t0DkbmzUjRK5JmUPdQyuqKl1QTfl9tCKEsEJToc_Qo5S6nFJayofojFaklJxXK_Rrk1JwYCcIIw4t3kwRbI93UEfo-1PZjg3eBZfL7_0cQx_24PAb34KDKeEvMH3Dl8PBQvQN3ob9CBPceLybR3crhxFfhHSAyfbwIyMfc1c_ZuWfn79lib96G9Pt6L1_jB60tk_-yfKeo8-7t5-2F8XVh3eX281V4QQjU1HyWoqaC0tFVTaSN9Iywl3OWlFVSntmqRUlVc5qV-u2rpnQPAu0UFYKxc_Ry1PfQwzXs0-TGSA5nz88-jAnI5VWRCiWwef_gF2Y45h3M4wTLimRNEPlCXIxpBR9aw4RBhu_G0rM0SzTmcUsczTLkDLHcYtnS_O5Hnxzp1rcycCLBbApn7-NdnSQ7jjFJKdSZO71ifP5Zjfgo0kun9j5JnviJtME-M8qfwE4S7XI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>230361061</pqid></control><display><type>article</type><title>Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age</title><source>Elsevier</source><creator>Jozwiak, Andrzej ; Guzik, Przemyslaw ; Mathew, Anup ; Wykretowicz, Andrzej ; Wysocki, Henryk</creator><creatorcontrib>Jozwiak, Andrzej ; Guzik, Przemyslaw ; Mathew, Anup ; Wykretowicz, Andrzej ; Wysocki, Henryk</creatorcontrib><description>Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for any reason and grouped according to the presence of AF and/or FNDs. Data on 2,314 conscious patients aged ≥65 years (1,506 women) were analyzed. Physical examination, electrocardiography at rest, and the Mini-Mental State Examination were performed at admission. The median Mini-Mental State Examination score was 25 in patients without AF or FNDs (63.4%), 23 in those with AF alone (23.6%), 21 in those with FNDs alone (8.9%), and 18 in those with AF and FNDs (4.1%). On multivariate logistic regression (adjusted for age and gender), the risk for ICF was increased in patients with AF alone (p &lt;0.0001), in those with FNDs alone (p &lt;0.0001), and in those with AF and FNDs (p &lt;0.0001). In conclusion, hospitalized patients aged ≥65 years with AF and/or FNDs at admission are at increased risk for ICF. The influences of AF and FNDs on the risk for ICF are independent of each other.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2006.05.058</identifier><identifier>PMID: 17056337</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Analysis of Variance ; Atrial Fibrillation - complications ; Atrial Fibrillation - physiopathology ; Biological and medical sciences ; Cardiac dysrhythmias ; Cardiology. Vascular system ; Cardiovascular disease ; Cognition &amp; reasoning ; Cognition Disorders - etiology ; Cognition Disorders - physiopathology ; Female ; Heart ; Hospitalization ; Humans ; Inpatients ; Male ; Medical sciences ; Nervous System Diseases - complications ; Nervous System Diseases - etiology ; Nervous System Diseases - physiopathology ; Neurology ; Neuropsychological Tests ; Older people ; Psychomotor Performance ; Retrospective Studies ; Risk Factors</subject><ispartof>The American journal of cardiology, 2006-11, Vol.98 (9), p.1238-1241</ispartof><rights>2006 Elsevier Inc.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. Nov 1, 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483</citedby><cites>FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=18263164$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17056337$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jozwiak, Andrzej</creatorcontrib><creatorcontrib>Guzik, Przemyslaw</creatorcontrib><creatorcontrib>Mathew, Anup</creatorcontrib><creatorcontrib>Wykretowicz, Andrzej</creatorcontrib><creatorcontrib>Wysocki, Henryk</creatorcontrib><title>Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for any reason and grouped according to the presence of AF and/or FNDs. Data on 2,314 conscious patients aged ≥65 years (1,506 women) were analyzed. Physical examination, electrocardiography at rest, and the Mini-Mental State Examination were performed at admission. The median Mini-Mental State Examination score was 25 in patients without AF or FNDs (63.4%), 23 in those with AF alone (23.6%), 21 in those with FNDs alone (8.9%), and 18 in those with AF and FNDs (4.1%). On multivariate logistic regression (adjusted for age and gender), the risk for ICF was increased in patients with AF alone (p &lt;0.0001), in those with FNDs alone (p &lt;0.0001), and in those with AF and FNDs (p &lt;0.0001). In conclusion, hospitalized patients aged ≥65 years with AF and/or FNDs at admission are at increased risk for ICF. The influences of AF and FNDs on the risk for ICF are independent of each other.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis of Variance</subject><subject>Atrial Fibrillation - complications</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Biological and medical sciences</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular disease</subject><subject>Cognition &amp; reasoning</subject><subject>Cognition Disorders - etiology</subject><subject>Cognition Disorders - physiopathology</subject><subject>Female</subject><subject>Heart</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Inpatients</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous System Diseases - complications</subject><subject>Nervous System Diseases - etiology</subject><subject>Nervous System Diseases - physiopathology</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Older people</subject><subject>Psychomotor Performance</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqFkc-KFDEQxoMo7rj6CEoQ9NZj_nU6OckwOu7Coh4U8RTS6fRYTXdnNule0Dfw4GP4Yj6JmZ2GBS9CQaji91VV6kPoKSVrSqh81a3t0DkbmzUjRK5JmUPdQyuqKl1QTfl9tCKEsEJToc_Qo5S6nFJayofojFaklJxXK_Rrk1JwYCcIIw4t3kwRbI93UEfo-1PZjg3eBZfL7_0cQx_24PAb34KDKeEvMH3Dl8PBQvQN3ob9CBPceLybR3crhxFfhHSAyfbwIyMfc1c_ZuWfn79lib96G9Pt6L1_jB60tk_-yfKeo8-7t5-2F8XVh3eX281V4QQjU1HyWoqaC0tFVTaSN9Iywl3OWlFVSntmqRUlVc5qV-u2rpnQPAu0UFYKxc_Ry1PfQwzXs0-TGSA5nz88-jAnI5VWRCiWwef_gF2Y45h3M4wTLimRNEPlCXIxpBR9aw4RBhu_G0rM0SzTmcUsczTLkDLHcYtnS_O5Hnxzp1rcycCLBbApn7-NdnSQ7jjFJKdSZO71ifP5Zjfgo0kun9j5JnviJtME-M8qfwE4S7XI</recordid><startdate>20061101</startdate><enddate>20061101</enddate><creator>Jozwiak, Andrzej</creator><creator>Guzik, Przemyslaw</creator><creator>Mathew, Anup</creator><creator>Wykretowicz, Andrzej</creator><creator>Wysocki, Henryk</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20061101</creationdate><title>Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age</title><author>Jozwiak, Andrzej ; Guzik, Przemyslaw ; Mathew, Anup ; Wykretowicz, Andrzej ; Wysocki, Henryk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analysis of Variance</topic><topic>Atrial Fibrillation - complications</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular disease</topic><topic>Cognition &amp; reasoning</topic><topic>Cognition Disorders - etiology</topic><topic>Cognition Disorders - physiopathology</topic><topic>Female</topic><topic>Heart</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Inpatients</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous System Diseases - complications</topic><topic>Nervous System Diseases - etiology</topic><topic>Nervous System Diseases - physiopathology</topic><topic>Neurology</topic><topic>Neuropsychological Tests</topic><topic>Older people</topic><topic>Psychomotor Performance</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jozwiak, Andrzej</creatorcontrib><creatorcontrib>Guzik, Przemyslaw</creatorcontrib><creatorcontrib>Mathew, Anup</creatorcontrib><creatorcontrib>Wykretowicz, Andrzej</creatorcontrib><creatorcontrib>Wysocki, Henryk</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jozwiak, Andrzej</au><au>Guzik, Przemyslaw</au><au>Mathew, Anup</au><au>Wykretowicz, Andrzej</au><au>Wysocki, Henryk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2006-11-01</date><risdate>2006</risdate><volume>98</volume><issue>9</issue><spage>1238</spage><epage>1241</epage><pages>1238-1241</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and can manifest as impaired cognitive function (ICF). ICF may be accompanied by various focal neurologic deficits (FNDs). This study evaluated cognitive function and the risk for ICF in patients aged ≥65 years hospitalized for any reason and grouped according to the presence of AF and/or FNDs. Data on 2,314 conscious patients aged ≥65 years (1,506 women) were analyzed. Physical examination, electrocardiography at rest, and the Mini-Mental State Examination were performed at admission. The median Mini-Mental State Examination score was 25 in patients without AF or FNDs (63.4%), 23 in those with AF alone (23.6%), 21 in those with FNDs alone (8.9%), and 18 in those with AF and FNDs (4.1%). On multivariate logistic regression (adjusted for age and gender), the risk for ICF was increased in patients with AF alone (p &lt;0.0001), in those with FNDs alone (p &lt;0.0001), and in those with AF and FNDs (p &lt;0.0001). In conclusion, hospitalized patients aged ≥65 years with AF and/or FNDs at admission are at increased risk for ICF. The influences of AF and FNDs on the risk for ICF are independent of each other.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17056337</pmid><doi>10.1016/j.amjcard.2006.05.058</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0002-9149
ispartof The American journal of cardiology, 2006-11, Vol.98 (9), p.1238-1241
issn 0002-9149
1879-1913
language eng
recordid cdi_proquest_miscellaneous_68980482
source Elsevier
subjects Age Factors
Aged
Aged, 80 and over
Analysis of Variance
Atrial Fibrillation - complications
Atrial Fibrillation - physiopathology
Biological and medical sciences
Cardiac dysrhythmias
Cardiology. Vascular system
Cardiovascular disease
Cognition & reasoning
Cognition Disorders - etiology
Cognition Disorders - physiopathology
Female
Heart
Hospitalization
Humans
Inpatients
Male
Medical sciences
Nervous System Diseases - complications
Nervous System Diseases - etiology
Nervous System Diseases - physiopathology
Neurology
Neuropsychological Tests
Older people
Psychomotor Performance
Retrospective Studies
Risk Factors
title Association of Atrial Fibrillation and Focal Neurologic Deficits With Impaired Cognitive Function in Hospitalized Patients ≥65 Years of Age
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T05%3A15%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20of%20Atrial%20Fibrillation%20and%20Focal%20Neurologic%20Deficits%20With%20Impaired%20Cognitive%20Function%20in%20Hospitalized%20Patients%20%E2%89%A565%20Years%20of%20Age&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Jozwiak,%20Andrzej&rft.date=2006-11-01&rft.volume=98&rft.issue=9&rft.spage=1238&rft.epage=1241&rft.pages=1238-1241&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2006.05.058&rft_dat=%3Cproquest_cross%3E1189808131%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c420t-53b64b34a1475d63d6a203c147f47789e2a1a4518ca9cb9fbb2493b34948a6483%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=230361061&rft_id=info:pmid/17056337&rfr_iscdi=true