Does preoperative mechanical ventilation affect outcomes in neonates undergoing cardiac surgery?

Objective: To review, in retrospective fashion, the effect of preoperative mechanical ventilation on neonatal outcomes after cardiac surgery. Methods: We studied 114 newborns less than 15 days old admitted to the cardiac intensive care unit for cardiac surgery. Of the newborns, 71 (62%) were mechani...

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Bibliographic Details
Published in:Cardiology in the young 2007-02, Vol.17 (1), p.90-94
Main Authors: Simsic, Janet M., Kanter, Kirk R., Kirshbom, Paul M., Cuadrado, Angel
Format: Article
Language:English
Subjects:
Cardiac Surgical Procedures
Congenital heart disease
Female
Hospitals
Humans
Hypoplastic Left Heart Syndrome - surgery
Infant, Newborn
Intensive care
Male
Mortality
neonatal outcomes
Original Article
Postoperative Complications - epidemiology
Preoperative Care
preoperative management
Respiration, Artificial
Retrospective Studies
Risk Factors
Sepsis - epidemiology
Surgery
Treatment Outcome
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Summary:Objective: To review, in retrospective fashion, the effect of preoperative mechanical ventilation on neonatal outcomes after cardiac surgery. Methods: We studied 114 newborns less than 15 days old admitted to the cardiac intensive care unit for cardiac surgery. Of the newborns, 71 (62%) were mechanically ventilated at the referring hospital before transport to our institution. Of the 71 ventilated patients, 14 were extubated and breathing spontaneously before cardiac surgery. We compared variable haemodynamics and outcomes between the 57 patients mechanically ventilated at time of cardiac surgery, and the 57 patients breathing spontaneously at this time. Results: Newborns mechanically ventilated before cardiac surgery had increased preoperative haemodynamic compromise, increased postoperative sepsis (p equal to 0.02) and mortality (p equal to 0.005) compared with those breathing spontaneously before cardiac surgery. Conclusion: Newborns requiring preoperative mechanical ventilation had greater risk of postoperative morbidity and mortality. Heightened vigilance is warranted in this population of patients at high risk.
ISSN:1047-9511
1467-1107
DOI:10.1017/S1047951107000091