The prognostic impact of successful cardioversion of atrial fibrillation in patients with organic heart disease

The aim of the study was to evaluate the prognostic impact of successful cardioversion (CV) compared to failed CV in patients with atrial fibrillation (AF) and organic heart disease. A total of 471 consecutive patients with organic heart disease from the prospective single center anticoagulation reg...

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Bibliographic Details
Published in:Clinical research in cardiology 2007-02, Vol.96 (2), p.103-108
Main Authors: Kleemann, T, Becker, T, Dönges, K, Vater, M, Gut, B, Schneider, S, Senges, J, Seidl, K
Format: Article
Language:English
Subjects:
Aged
Atrial Fibrillation - etiology
Atrial Fibrillation - mortality
Atrial Fibrillation - therapy
Atrial Flutter - etiology
Atrial Flutter - mortality
Atrial Flutter - therapy
Cardiac arrhythmia
Cardiology
Cardiovascular disease
Electric Countershock
Female
Follow-Up Studies
Heart Diseases - complications
Humans
Male
Middle Aged
Mortality
Multivariate analysis
Prognosis
Prospective Studies
Survival Analysis
Treatment Outcome
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Summary:The aim of the study was to evaluate the prognostic impact of successful cardioversion (CV) compared to failed CV in patients with atrial fibrillation (AF) and organic heart disease. A total of 471 consecutive patients with organic heart disease from the prospective single center anticoagulation registry ANTIK who underwent CV of AF or atrial flutter were analyzed. 417 patients (89%) could be successfully cardioverted. In 54 patients (11%) CV failed, these patients remained in AF. After 5 years there were 92 (24%) deaths among patients with restored sinus rhythm at index admission and 20 (38%) deaths among those who remained in AF after CV (unadjusted OR 1.9, 95% CI 1.1-3.6). After adjustment for age, gender and ejection fraction, successful CV was not associated with a beneficial effect on mortality (OR 0.72, 95% CI 0.43-1.21). Thus, successful CV is not an independent predictor of mortality on multivariate analysis. However, it remains a marker for a better prognosis in patients with organic heart disease as these patients have a lower unadjusted longterm mortality.
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-006-0466-8