Stereotactic surgery for subthalamic nucleus stimulation under general anesthesia: A retrospective evaluation of Japanese patients with Parkinson's disease

Abstract We compared retrospectively the outcome of bilateral subthalamic nucleus (STN) stimulation in 15 patients with Parkinson's disease who underwent the procedure under general anesthesia (GA) with that achieved in 10 patients under local anesthesia (LA). At 3 months postoperatively, all c...

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Bibliographic Details
Published in:Parkinsonism & related disorders 2007-03, Vol.13 (2), p.101-107
Main Authors: Yamada, Kazumichi, Goto, Satoshi, Kuratsu, Jun-ichi, Matsuzaki, Kazuhito, Tamura, Tetsuya, Nagahiro, Shinji, Murase, Nagako, Shimazu, Hideki, Kaji, Ryuji
Format: Article
Language:English
Subjects:
Aged
Anesthesia - methods
Anxiety
Deep brain stimulation
Deep Brain Stimulation - methods
Drug-induced psychosis
Female
General anesthesia
Humans
Japan - ethnology
Male
Middle Aged
Neurology
Parkinson Disease - pathology
Parkinson Disease - surgery
Parkinson's disease
Retrospective Studies
Stereotaxic Techniques
Subthalamic nucleus
Subthalamic Nucleus - surgery
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Summary:Abstract We compared retrospectively the outcome of bilateral subthalamic nucleus (STN) stimulation in 15 patients with Parkinson's disease who underwent the procedure under general anesthesia (GA) with that achieved in 10 patients under local anesthesia (LA). At 3 months postoperatively, all cardinal parkinsonian motor symptoms, evaluated on Unified Parkinson's Disease Rating Scale were significantly improved compared to preoperative baselines in both groups. The administration of GA did not adversely affect postoperative improvements in motor and daily activity scores, except for off-medication bradykinesia. Our results suggest that GA compares favorably with LA in surgical procedure for bilateral STN stimulation.
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2006.07.008