Polyphenol-enriched oolong tea increases fecal lipid excretion

Objective: To assess possibility of polyphenol-enriched oolong tea to reduce dietary lipid absorption in humans. Design: Twelve healthy adult subjects, three males and nine females, aged (mean +/- s.d.) 22.0 +/- 1.8 years, respectively, were randomly divided into two groups. The participants were fo...

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Bibliographic Details
Published in:European journal of clinical nutrition 2006-11, Vol.60 (11), p.1330-1336
Main Authors: Hsu, T.F, Kusumoto, A, Abe, K, Hosoda, K, Kiso, Y, Wang, M.F, Yamamoto, S
Format: Article
Language:English
Subjects:
Absorption
Adult
Antioxidants
Beverages
Biological and medical sciences
Blood
Cholesterol
Cholesterol - analysis
Cholesterol - metabolism
Clinical Nutrition
Clinical outcomes
clinical trials
Cross-Over Studies
defecation
Design
Diet
dietary fat
Dietary Fats - administration & dosage
Dietary Fats - pharmacokinetics
Double-Blind Method
enriched foods
Enrichment
Epidemiology
Excretion
experimental diets
fat intake
Feces
Feces - chemistry
Female
Flavonoids - pharmacology
Food, Fortified
high fat diet
Humans
Hypercholesterolemia - diet therapy
Internal Medicine
intestinal absorption
Intestinal Absorption - drug effects
lipid metabolism
Lipids
Lipids - analysis
Male
Meals
Medical sciences
Medicine
Medicine & Public Health
men
Metabolic Diseases
Nutrition
nutrition research
Obesity - diet therapy
Oolong tea
original-article
Phenols - pharmacology
Placebos
Polyphenols
Potatoes
Public Health
Tea
tea (beverage)
weight loss
women
young adults
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Summary:Objective: To assess possibility of polyphenol-enriched oolong tea to reduce dietary lipid absorption in humans. Design: Twelve healthy adult subjects, three males and nine females, aged (mean +/- s.d.) 22.0 +/- 1.8 years, respectively, were randomly divided into two groups. The participants were followed a double-blind placebo-controlled crossover design, including 7-day washout periods and 10-day treatment periods. During the treatment periods, subjects were given about 38 g of lipids from potato chips (19 g each within 30 min after lunch and dinner) and total 750 ml beverages (placebo- or polyphenol-enriched oolong tea) at three meals. Blood samples were collected for biochemical examination at days 8, 18, 25 and 35 of the study period. On the last 3 days of each treatment period, feces were collected to measure the excretion of lipids. Results: Lipid excretion into feces was significantly higher in the polyphenol-enriched oolong tea period (19.3 +/- 12.9 g/3day) than in the placebo period (9.4 +/- 7.3 g/3day) (P
ISSN:0954-3007
1476-5640
DOI:10.1038/sj.ejcn.1602464