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The Effect of Patient Age and Other Factors on the Maintenance of Permanent Hemodialysis Vascular Access

:  The objective of the present study was to investigate whether patient age is associated with vascular access failure during maintenance hemodialysis. Thus, patients who had a successful permanent hemodialysis vascular access installed (Group N: 314 cases), and those who required vascular access r...

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Published in:Therapeutic apheresis and dialysis 2007-02, Vol.11 (1), p.36-41
Main Authors: Hayakawa, Kunihiro, Miyakawa, Shinzaburo, Hoshinaga, Kiyotaka, Hata, Kenichi, Marumo, Ken, Hata, Makoto
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container_title Therapeutic apheresis and dialysis
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creator Hayakawa, Kunihiro
Miyakawa, Shinzaburo
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Hata, Makoto
description :  The objective of the present study was to investigate whether patient age is associated with vascular access failure during maintenance hemodialysis. Thus, patients who had a successful permanent hemodialysis vascular access installed (Group N: 314 cases), and those who required vascular access revision (Group R: 108 patients) were studied. To assess the association between patient age and the risk of vascular access failure, Cox proportional hazards regression was used to determine hazard ratios (HR) and 95% confidence intervals (CI). We found that in Group N, the significant risk factors were age, gender, and diabetes mellitus (95% CI: 1.004–1.013, 0.380–0.827, 1.279–2.859). Using a univariate analysis model, significant hazard ratios (HR) were found with ages of 60 (CI: 1.062–2.302), 65 (CI: 1.052–2.280), and 70 (CI: 1.082–2.537) years, with the largest HR at 70 years of age (HR: 1.657). In contrast, in Group R, multivariate analysis using Cox proportional hazards identified only one prognostic variable, the location of the vascular access. In Group R, univariate analysis models showed that age was not a significant factor. We conclude that our data show that age is a risk factor for the successful maintenance of initial permanent hemodialysis vascular access. Other risk factors include gender and diabetes mellitus. However, these factors were not related to the successful maintenance of revised vascular access.
doi_str_mv 10.1111/j.1744-9987.2007.00453.x
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source Wiley-Blackwell Read & Publish Collection
subjects Adult
Age Factors
Aged
Aged, 80 and over
Arteriovenous Shunt, Surgical
Female
Humans
Male
Middle Aged
Multivariate Analysis
Patient age
Prognosis
Proportional Hazards Models
Renal Dialysis
Risk factor
Risk Factors
Survival rate
Vascular access
title The Effect of Patient Age and Other Factors on the Maintenance of Permanent Hemodialysis Vascular Access
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