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Primary Carcinosarcoma of the Helix of the Ear

We report our histologic and immunohistochemical findings in a rare case of cutaneous carcinosarcoma involving the helix of the ear. The tumor exhibited cellular features of both basal cell and squamous cell carcinoma and a malignant mesenchymal component that was consistent with malignant fibrous h...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2005-11, Vol.84 (11), p.712-715
Main Authors: Vincek, Vladimir, Mirzabeigi, Marjan, Jewett, Brian S., Goodwin, W. Jarrard
Format: Article
Language:English
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Summary:We report our histologic and immunohistochemical findings in a rare case of cutaneous carcinosarcoma involving the helix of the ear. The tumor exhibited cellular features of both basal cell and squamous cell carcinoma and a malignant mesenchymal component that was consistent with malignant fibrous histiocytoma. The epithelial component exhibited a positive immunohistochemical reaction to cytokeratin and a negative reaction to vimentin, whereas the mesenchymal component showed a positive immunohistochemical reaction to vimentin and a negative reaction to cytokeratin. To the best of our knowledge, this is only the third reported case of a carcinosarcoma of the ear and the second case in which it developed on the helix.
ISSN:0145-5613
1942-7522
DOI:10.1177/014556130508401112