Short-term femoral venous dialysis catheters for autologous peripheral blood progenitor cell collection: Retrospective evaluation in 276 catheter practice from a single center

Abstract We retrospectively evaluated 276 short-term femoral venous dialysis catheters (STFVCs) used for the collection of peripheral blood progenitor cells (PBPCs). Patients were not given any prophylactic antibiotic or anti-thrombotic therapy. Totally 877 leukapheresis sessions were performed. STF...

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Bibliographic Details
Published in:Transfusion and apheresis science 2007-10, Vol.37 (2), p.165-169
Main Authors: Donmez, Ayhan, Cagirgan, Seckin, Tombuloglu, Murat
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Autologous PBPC collection
Catheter associated complications
Catheterization, Central Venous - adverse effects
Catheterization, Central Venous - instrumentation
Catheterization, Central Venous - methods
Ecchymosis - etiology
Female
Femoral vascular access
Femoral Vein
Health technology assessment
Hematology, Oncology and Palliative Medicine
Hematoma - etiology
Hematopoietic Stem Cell Mobilization - adverse effects
Hematopoietic Stem Cell Mobilization - methods
Humans
Leukapheresis - instrumentation
Leukapheresis - methods
Male
Middle Aged
Peripheral Blood Stem Cell Transplantation - adverse effects
Retrospective Studies
Transplantation, Autologous
Treatment Outcome
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Summary:Abstract We retrospectively evaluated 276 short-term femoral venous dialysis catheters (STFVCs) used for the collection of peripheral blood progenitor cells (PBPCs). Patients were not given any prophylactic antibiotic or anti-thrombotic therapy. Totally 877 leukapheresis sessions were performed. STFVCs were sufficient for continuous flow rate in all leukapheresis session. Side effects were detected in 30 (10.86%) STFVC practice (ecchymosis and/or hematoma in 13 (4.71%), thrombophlebitis in 5 (1.81%), bleeding in 4 (1.44%), catheters were not inserted into right femoral vein in 4 (1.44%), infection in PBPC products of 3 (1.08%) and blood receiving tip of catheter was cracked in 1 (0.36%)). Our results showed that STFVCs minimized the serious side effects such as thrombophlebitis, bleeding and infection of PBPC products. The STFVCs appeared safe and effective for PBPC collection.
ISSN:1473-0502
1878-1683
DOI:10.1016/j.transci.2007.08.004