Ventricular tachycardia in a neonate with prenatally diagnosed cardiac tumors: a case with tuberous sclerosis

We report a patient with prenatally diagnosed tuberous sclerosis. Fetal ultrasonography demonstrated multiple cardiac tumors and arrhythmia. After birth, because of frequent supraventricular extrasystoles, the infant was admitted to the neonatal intensive care unit. Findings on 24-hour ambulatory el...

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Bibliographic Details
Published in:Pediatric cardiology 2005-10, Vol.26 (5), p.655-657
Main Authors: Hirakubo, Y, Ichihashi, K, Shiraishi, H, Momoi, M Y
Format: Article
Language:English
Subjects:
Adrenergic beta blockers
Adult
Anti-Arrhythmia Agents - therapeutic use
Carteolol - therapeutic use
Case studies
Diagnosis
Dosage and administration
Drug therapy
Echocardiography, Doppler, Color
Electrocardiography
Female
Fetal Diseases - diagnosis
Fetal Diseases - drug therapy
Heart Neoplasms - diagnosis
Heart Neoplasms - drug therapy
Humans
Infant, Newborn
Male
Pregnancy
Prenatal Diagnosis
Tachycardia, Ventricular - diagnosis
Tachycardia, Ventricular - drug therapy
Tuberous sclerosis
Tuberous Sclerosis - diagnosis
Tuberous Sclerosis - drug therapy
Ventricular Fibrillation - diagnosis
Ventricular Fibrillation - drug therapy
Ventricular tachycardia
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Summary:We report a patient with prenatally diagnosed tuberous sclerosis. Fetal ultrasonography demonstrated multiple cardiac tumors and arrhythmia. After birth, because of frequent supraventricular extrasystoles, the infant was admitted to the neonatal intensive care unit. Findings on 24-hour ambulatory electrocardiogram (ECG) showed frequent supraventricular tachycardia and ventricular tachycardia with four beats as the longest run. At the age of 12 days, he developed cardiopulmonary arrest after crying out. A monitored ECG showed ventricular tachycardia. Twenty minutes after onset, a 12-lead ECG showed ventricular fibrillation, which returned to normal sinus rhythm with repeated DC cardioversion. Oral antiarrhythmic therapy with carteolol hydrochloride was effective. The patient showed no further symptoms after oral medication was initiated and the tumors regressed spontaneously.
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-004-0714-5