Polymorphous Low-Grade Adenocarcinoma at the Base of the Tongue: An Unusual Location

Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those in the palate. We report a case of PLGA that arose in the base of the tongue and subsequently metastasized to the neck. The tumor wa...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2005-12, Vol.84 (12), p.794-799
Main Authors: Tincani, Alfio J., Altemani, Albina, Martins, Antonio S., Barreto, Gilson, Valério, João B., Del Negro, André, Araújo, Priscila P.C.
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenocarcinoma - pathology
Aged
Cancer
Care and treatment
Case studies
Humans
Male
Oncology, Experimental
Radiotherapy
Tongue Neoplasms - pathology
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Summary:Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those in the palate. We report a case of PLGA that arose in the base of the tongue and subsequently metastasized to the neck. The tumor was resected through the oral cavity with wide margins and dissection. The neck metastasis was treated with radical neck dissection and radiotherapy. The patient recovered and remained disease-free at follow-up 30 months later. This case shows that PLGA, which has a variable morphologic appearance, can occur at sites other than the salivary glands.
ISSN:0145-5613
1942-7522
DOI:10.1177/014556130508401219