Dielectrophoresis for the manipulation of nanobioparticles

Dielectrophoresis (DEP) is a nondestructive electrokinetic mechanism with great potential for the manipulation of bioparticles. DEP is the movement of particles induced by polarization effects in nonuniform electric fields. Since the 1960s, this technique has been successfully used for the manipulat...

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Bibliographic Details
Published in:Electrophoresis 2007-12, Vol.28 (24), p.4521-4538
Main Authors: Lapizco-Encinas, Blanca H, Rito-Palomares, Marco
Format: Article
Language:English
Subjects:
Biotechnology
Dielectrophoresis
DNA
DNA - isolation & purification
Electrophoresis - methods
Mosaic Viruses - isolation & purification
Nanobioparticles
Nanoparticles
Proteins
Proteins - isolation & purification
Simplexvirus - isolation & purification
Virus
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Summary:Dielectrophoresis (DEP) is a nondestructive electrokinetic mechanism with great potential for the manipulation of bioparticles. DEP is the movement of particles induced by polarization effects in nonuniform electric fields. Since the 1960s, this technique has been successfully used for the manipulation of microbioparticles, such as microorganisms. Moreover, due to the advances in microfabrication techniques, that allowed progressively smaller microstructures to be constructed, DEP can now be used for the manipulation of nanobioparticles. The first research studies on the DEP of nanobioparticles started in the 1990s. Since then, many research groups have carried out outstanding work with DEP of nanobioparticles such as macromolecules, virus, and spores. However, the need of a critical report that integrates these findings is evident. The aim of the present review is to depict the state-of-the-art on the use of DEP for the separation of nanobioparticles and the potential trends of novel applications of this technique. This review compiles and analyzes the significant findings obtained by many researchers. This publication is intended to provide the reader with state-of-the-art information on many research studies focused on DEP to handle nanobioparticles.
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.200700303