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Histological study of granulated metrial gland (GMC) cells in beige (DA-bg/bg) rats
To clarify the roles of granulated metrial gland (GMG) cells for successful pregnancy in rats, GMG cells in beige rats (genotype: DA-bg/bg), whose NK cells show lysosomal dysfunction because of abnormalities in cytoplasmic granules, were examined in mid- and late-pregnancy by light and electron micr...
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| Published in: | Journal of Reproduction and Development 2005, Vol.51(6), pp.799-803 |
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| container_end_page | 803 |
| container_issue | 6 |
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| container_title | Journal of Reproduction and Development |
| container_volume | 51 |
| creator | Hondo, E.(Yamaguchi Univ. (Japan)) Kokubo, K Nagahisa, A Nakamuta, N Ozaki, K Sagara, E Kiso, Y |
| description | To clarify the roles of granulated metrial gland (GMG) cells for successful pregnancy in rats, GMG cells in beige rats (genotype: DA-bg/bg), whose NK cells show lysosomal dysfunction because of abnormalities in cytoplasmic granules, were examined in mid- and late-pregnancy by light and electron microscopies. The GMG cells of beige rats were significantly less in number than those of the two controls (genotypes: DA-bg/+ and DA-+1+) in mid- and late-pregnancy, and this accompanied a 10w reproductive performance in the beige rats. The size of intracellular granules in the GMG cells of the beige rats was larger than for the two controls on each corresponding day of pregnancy. These results suggest that the activity of rat GMG cells and peripheral NK cells might be influenced by the beige gene, which is involved in reproductive performance. |
| doi_str_mv | 10.1262/jrd.17048 |
| format | article |
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(Japan)) ; Kokubo, K ; Nagahisa, A ; Nakamuta, N ; Ozaki, K ; Sagara, E ; Kiso, Y</creator><creatorcontrib>Hondo, E.(Yamaguchi Univ. (Japan)) ; Kokubo, K ; Nagahisa, A ; Nakamuta, N ; Ozaki, K ; Sagara, E ; Kiso, Y</creatorcontrib><description>To clarify the roles of granulated metrial gland (GMG) cells for successful pregnancy in rats, GMG cells in beige rats (genotype: DA-bg/bg), whose NK cells show lysosomal dysfunction because of abnormalities in cytoplasmic granules, were examined in mid- and late-pregnancy by light and electron microscopies. The GMG cells of beige rats were significantly less in number than those of the two controls (genotypes: DA-bg/+ and DA-+1+) in mid- and late-pregnancy, and this accompanied a 10w reproductive performance in the beige rats. The size of intracellular granules in the GMG cells of the beige rats was larger than for the two controls on each corresponding day of pregnancy. These results suggest that the activity of rat GMG cells and peripheral NK cells might be influenced by the beige gene, which is involved in reproductive performance.</description><identifier>ISSN: 0916-8818</identifier><identifier>EISSN: 1348-4400</identifier><identifier>DOI: 10.1262/jrd.17048</identifier><identifier>PMID: 16210783</identifier><language>eng</language><publisher>Japan: THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</publisher><subject>Animals ; Beige rat ; Cell Differentiation ; CELLS ; CELLULE ; CELULAS ; Cytoplasmic Granules - pathology ; Cytoplasmic Granules - ultrastructure ; Female ; GENE ; GENES ; GESTATION PERIOD ; Granulated metrial gland (GMG) cell ; LINFOCITOS ; LYMPHOCYTE ; LYMPHOCYTES ; Lysosomes - pathology ; Lysosomes - ultrastructure ; Metrial Gland - pathology ; Metrial Gland - ultrastructure ; MICROSCOPIA ; MICROSCOPIE ; MICROSCOPY ; Microscopy, Electron ; PERFORMANCE DE REPRODUCTION ; PERIODE DE GESTATION ; PERIODO DE GESTACION ; Pregnancy ; Proteins - genetics ; RAT ; RATA ; RATS ; Rats, Mutant Strains ; Reproduction - physiology ; REPRODUCTIVE PERFORMANCE ; REPRODUCTIVIDAD ; UTERO ; UTERUS</subject><ispartof>Journal of Reproduction and Development, 2005, Vol.51(6), pp.799-803</ispartof><rights>2005 Society for Reproduction and Development</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c491t-5d8ab8863b080af7c72c7b5f3aa8f4d1ab776a3068bc6dd556eda6f621bbab283</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16210783$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hondo, E.(Yamaguchi Univ. 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The GMG cells of beige rats were significantly less in number than those of the two controls (genotypes: DA-bg/+ and DA-+1+) in mid- and late-pregnancy, and this accompanied a 10w reproductive performance in the beige rats. The size of intracellular granules in the GMG cells of the beige rats was larger than for the two controls on each corresponding day of pregnancy. These results suggest that the activity of rat GMG cells and peripheral NK cells might be influenced by the beige gene, which is involved in reproductive performance.</description><subject>Animals</subject><subject>Beige rat</subject><subject>Cell Differentiation</subject><subject>CELLS</subject><subject>CELLULE</subject><subject>CELULAS</subject><subject>Cytoplasmic Granules - pathology</subject><subject>Cytoplasmic Granules - ultrastructure</subject><subject>Female</subject><subject>GENE</subject><subject>GENES</subject><subject>GESTATION PERIOD</subject><subject>Granulated metrial gland (GMG) cell</subject><subject>LINFOCITOS</subject><subject>LYMPHOCYTE</subject><subject>LYMPHOCYTES</subject><subject>Lysosomes - pathology</subject><subject>Lysosomes - ultrastructure</subject><subject>Metrial Gland - pathology</subject><subject>Metrial Gland - ultrastructure</subject><subject>MICROSCOPIA</subject><subject>MICROSCOPIE</subject><subject>MICROSCOPY</subject><subject>Microscopy, Electron</subject><subject>PERFORMANCE DE REPRODUCTION</subject><subject>PERIODE DE GESTATION</subject><subject>PERIODO DE GESTACION</subject><subject>Pregnancy</subject><subject>Proteins - genetics</subject><subject>RAT</subject><subject>RATA</subject><subject>RATS</subject><subject>Rats, Mutant Strains</subject><subject>Reproduction - physiology</subject><subject>REPRODUCTIVE PERFORMANCE</subject><subject>REPRODUCTIVIDAD</subject><subject>UTERO</subject><subject>UTERUS</subject><issn>0916-8818</issn><issn>1348-4400</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNpFkE1LxDAQhoMoun4c_AFKTuIeqknTpulJZNVVURTUc5h8tGbptmuSHvbfW-2iMMwc3oeH4UXomJILmvL0cuHNBS1IJrbQhLJMJFlGyDaakJLyRAgq9tB-CAtCWJrzbBftUZ5SUgg2QW_3LsSu6WqnocEh9maNuwrXHtq-gWgNXtro3ZDVDbQGn8-fZ1OsbdME7FqsrKstPr-5TlR9qeop9hDDIdqpoAn2aHMP0Mfd7fvsPnl6mT_Mrp8SnZU0JrkRoITgTBFBoCp0kepC5RUDEFVmKKii4MAIF0pzY_KcWwO8Gl5XClQq2AE6G70r3331NkS5dOHnNWht1wfJS8J5nqcDOB1B7bsQvK3kyrsl-LWkRP40KIcG5W-DA3u6kfZqac0_ualsAK5GYBEi1PYPAB-dbuyvKqeSj6soy79Ef4KXth0MJ6Ohgk5C7V2Qj68pIXwYygT7Br1Wio8</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>Hondo, E.(Yamaguchi Univ. 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(Japan))</creatorcontrib><creatorcontrib>Kokubo, K</creatorcontrib><creatorcontrib>Nagahisa, A</creatorcontrib><creatorcontrib>Nakamuta, N</creatorcontrib><creatorcontrib>Ozaki, K</creatorcontrib><creatorcontrib>Sagara, E</creatorcontrib><creatorcontrib>Kiso, Y</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Reproduction and Development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hondo, E.(Yamaguchi Univ. 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The GMG cells of beige rats were significantly less in number than those of the two controls (genotypes: DA-bg/+ and DA-+1+) in mid- and late-pregnancy, and this accompanied a 10w reproductive performance in the beige rats. The size of intracellular granules in the GMG cells of the beige rats was larger than for the two controls on each corresponding day of pregnancy. These results suggest that the activity of rat GMG cells and peripheral NK cells might be influenced by the beige gene, which is involved in reproductive performance.</abstract><cop>Japan</cop><pub>THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</pub><pmid>16210783</pmid><doi>10.1262/jrd.17048</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0916-8818 |
| ispartof | Journal of Reproduction and Development, 2005, Vol.51(6), pp.799-803 |
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| language | eng |
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| source | Directory of Open Access Journals |
| subjects | Animals Beige rat Cell Differentiation CELLS CELLULE CELULAS Cytoplasmic Granules - pathology Cytoplasmic Granules - ultrastructure Female GENE GENES GESTATION PERIOD Granulated metrial gland (GMG) cell LINFOCITOS LYMPHOCYTE LYMPHOCYTES Lysosomes - pathology Lysosomes - ultrastructure Metrial Gland - pathology Metrial Gland - ultrastructure MICROSCOPIA MICROSCOPIE MICROSCOPY Microscopy, Electron PERFORMANCE DE REPRODUCTION PERIODE DE GESTATION PERIODO DE GESTACION Pregnancy Proteins - genetics RAT RATA RATS Rats, Mutant Strains Reproduction - physiology REPRODUCTIVE PERFORMANCE REPRODUCTIVIDAD UTERO UTERUS |
| title | Histological study of granulated metrial gland (GMC) cells in beige (DA-bg/bg) rats |
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