The effect of an ultra-endurance running race on mucosal and humoral immune function

There are reports of the effect of endurance exercise on mucosal immune function and of the effect of short duration exercise on humoral immune function. However, little is known of the effect of endurance exercise on humoral immune function and the related risk of infection. This study examined the...

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Bibliographic Details
Published in:Journal of sports medicine and physical fitness 2007-12, Vol.47 (4), p.496-501
Main Authors: PACQUE, P. F. J, BOOTH, C. K, BALL, M. J, DWYER, D. B
Format: Article
Language:English
Subjects:
Adult
Antibody Formation - immunology
Biological and medical sciences
Body Composition
Changes
Ethics
Female
Fundamental and applied biological sciences. Psychology
Humans
Immune system
Immunity, Mucosal
Immunoassay
Immunocompetence - immunology
Immunoglobulin A, Secretory - metabolism
International Organizations
Leukocytes - metabolism
Male
Middle Aged
Physical Activities
Physical Endurance - physiology
Physical fitness
Respiratory Tract Infections - epidemiology
Running
Running - physiology
Safety Equipment
Saliva
Sample size
Scientific Concepts
Sports medicine
Standard deviation
Tasmania - epidemiology
Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
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Summary:There are reports of the effect of endurance exercise on mucosal immune function and of the effect of short duration exercise on humoral immune function. However, little is known of the effect of endurance exercise on humoral immune function and the related risk of infection. This study examined the effects of an ultra-endurance running race on salivary immunoglobulin-A (s-IgA), serum IgA, leukocyte subset concentrations and the incidence of upper respiratory tract infections (URTI). Thirteen male and 4 female competitors provided saliva samples and blood before and at several times after the running race. Self-reported symptoms of URTI were also recorded for 2 weeks before and 2 weeks after the race. Salivary IgA secretion rate (P=0.005) and ratio to osmolality (P=0.006) were lower immediately postrace and decreased further for at least 2 more h. s-IgA secretion rate had not returned to normal the next morning (P=0.009). Serum IgA concentration was lower post- than prerace (P=0.003) and was even lower the next morning (P
ISSN:0022-4707
1827-1928