The dependence of thrombocyte aggregation on temperature

The effect of temperature (range of 4-44 degrees C) upon induced aggregation of platelets from normal subjects was studied. It was shown that temperature dependences of aggregation degree and rate have maxima. A relationship between aggregation agonist kind and some features of the temperature depen...

Full description

Saved in:
Bibliographic Details
Published in:Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 1998, Vol.44 (5-6), p.89-94
Main Authors: Berest, V P, Hatash, S V
Format: Article
Language:Ukrainian
Subjects:
Adenosine Diphosphate - pharmacology
Anti-Bacterial Agents - pharmacology
Dose-Response Relationship, Drug
Epinephrine - pharmacology
Female
Humans
Hydrogen Peroxide - pharmacology
Male
Platelet Aggregation - drug effects
Platelet Aggregation - physiology
Reference Values
Ristocetin - pharmacology
Temperature
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The effect of temperature (range of 4-44 degrees C) upon induced aggregation of platelets from normal subjects was studied. It was shown that temperature dependences of aggregation degree and rate have maxima. A relationship between aggregation agonist kind and some features of the temperature dependence curve of the aggregation parameters is established. It was shown that the limitation of platelet membrane lipids mobility by means of lipids peroxidation leads to the shift of maxima of the temperature dependence curve of platelet aggregation degree and rate. It was concluded that character of aggregation temperature dependence was governed by phase transition in platelet membrane lipids at room temperature.
ISSN:2522-9028