The cyanoacrylate topical skin adhesives

Abstract Each year there are over 7 million lacerations requiring wound closure in the emergency department. Traditionally, most lacerations have been closed with sutures. Topical cyanoacrylate skin adhesives offer many advantages over traditional wound closure devices. Recently, the Food and Drug A...

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Bibliographic Details
Published in:The American journal of emergency medicine 2008-05, Vol.26 (4), p.490-496
Main Authors: Singer, Adam J., MD, Quinn, James V., MD, MS, Hollander, Judd E., MD
Format: Article
Language:English
Subjects:
Adhesives
Administration, Topical
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Approximation
Biological and medical sciences
Bond strength
Cyanoacrylates - administration & dosage
Cyanoacrylates - pharmacology
Emergency
Emergency medical care
FDA approval
Humans
Infections
Intensive care medicine
Lacerations - therapy
Local anesthesia. Pain (treatment)
Medical sciences
Suture Techniques
Sutures
Tensile strength
Tissue Adhesives - administration & dosage
Tissue Adhesives - pharmacology
Toxicity
Wounds and Injuries - therapy
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Description
Summary:Abstract Each year there are over 7 million lacerations requiring wound closure in the emergency department. Traditionally, most lacerations have been closed with sutures. Topical cyanoacrylate skin adhesives offer many advantages over traditional wound closure devices. Recently, the Food and Drug Administration (FDA) has reclassified the topical skin adhesives. As a result, new topical skin adhesives are expected to enter the market in the near future. This article will review the structure and function of cyanoacrylates as well as their advantages, indications, and usage.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2007.05.015