Systemic mast cell disease associated with primary ovarian mixed malignant germ cell tumor

A 12-year-old girl with a mixed malignant germ cell tumor of the ovary, treated by surgery and chemotherapy, developed systemic mast cell disease (SMCD) approximately 3 months after chemotherapy. Hematologic malignancies have previously been noted in patients with mediastinal germ cell tumors but th...

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Bibliographic Details
Published in:Human pathology 1998-12, Vol.29 (12), p.1546-1547
Main Authors: Teitell, Michael, Rowland, Jon M
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child
Fatal Outcome
Female
Female genital diseases
Germ cell tumor
Germinoma - complications
Germinoma - pathology
Gynecology. Andrology. Obstetrics
Humans
mastocytosis
Mastocytosis - complications
Mastocytosis - pathology
Medical sciences
Mixed Tumor, Malignant - complications
Mixed Tumor, Malignant - pathology
Ovarian Neoplasms - complications
Ovarian Neoplasms - pathology
ovary
systemic mast cell disease
Tumors
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Description
Summary:A 12-year-old girl with a mixed malignant germ cell tumor of the ovary, treated by surgery and chemotherapy, developed systemic mast cell disease (SMCD) approximately 3 months after chemotherapy. Hematologic malignancies have previously been noted in patients with mediastinal germ cell tumors but this is the first report of a primary ovarian germ cell neoplasm associated with SMCD.
ISSN:0046-8177
1532-8392
DOI:10.1016/S0046-8177(98)90029-6