MR imaging methods for assessing fetal brain development

Fetal magnetic resonance imaging provides an ideal tool for investigating growth and development of the brain in vivo. Current imaging methods have been hampered by fetal motion but recent advances in image acquisition can produce high signal to noise, high resolution 3‐dimensional datasets suitable...

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Bibliographic Details
Published in:Developmental neurobiology (Hoboken, N.J.) N.J.), 2008-05, Vol.68 (6), p.700-711
Main Authors: Rutherford, Mary, Jiang, Shuzhou, Allsop, Joanna, Perkins, Lucinda, Srinivasan, Latha, Hayat, Tayyib, Kumar, Sailesh, Hajnal, Jo
Format: Article
Language:English
Subjects:
brain
Brain - anatomy & histology
Brain - embryology
fetal
Fetal Development - physiology
Fetus
Humans
Image Processing, Computer-Assisted
magnetic resonance imaging
Magnetic Resonance Imaging - methods
Prenatal Diagnosis
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Summary:Fetal magnetic resonance imaging provides an ideal tool for investigating growth and development of the brain in vivo. Current imaging methods have been hampered by fetal motion but recent advances in image acquisition can produce high signal to noise, high resolution 3‐dimensional datasets suitable for objective quantification by state of the art post acquisition computer programs. Continuing development of imaging techniques will allow a unique insight into the developing brain, more specifically process of cell migration, axonal pathway formation, and cortical maturation. Accurate quantification of these developmental processes in the normal fetus will allow us to identify subtle deviations from normal during the second and third trimester of pregnancy either in the compromised fetus or in infants born prematurely. © 2008 Wiley Periodicals, Inc. Develop Neurobiol, 2008
ISSN:1932-8451
1932-846X
DOI:10.1002/dneu.20614