Myocardial infarction and cerebrovascular accident following non‐cardiac surgery: differences in postoperative temporal distribution and risk factors

Background: Myocardial infarction and stroke after non‐cardiac surgery are two ominous cardiovascular complications believed to share similar pathophysiological processes. However, the differences in the temporal distribution between them have not been adequately investigated in a large cohort of pa...

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Published in:Journal of thrombosis and haemostasis 2008-05, Vol.6 (5), p.742-748
Main Authors: KIKURA, M., OIKAWA, F., YAMAMOTO, K., IWAMOTO, T., TANAKA, K. A., SATO, S., LANDESBERG, G.
Format: Article
Language:English
Subjects:
Age Factors
Aged
Cohort Studies
Female
Humans
ischemic stroke
Male
Middle Aged
myocardial infarction
Myocardial Infarction - etiology
non‐cardiac surgery
Postoperative Complications - etiology
Regression Analysis
Risk Factors
Sex Factors
Stroke - etiology
Time Factors
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Summary:Background: Myocardial infarction and stroke after non‐cardiac surgery are two ominous cardiovascular complications believed to share similar pathophysiological processes. However, the differences in the temporal distribution between them have not been adequately investigated in a large cohort of patients. Methods and Results: The preoperative clinical features and daily occurrence of myocardial infarction and stroke were routinely recorded in 36 634 consecutive patients following elective non‐cardiac, non‐carotid surgery. The preoperative characteristics and postoperative daily distribution of postoperative myocardial infarction and stroke were compared using exponential and linear regressions models. Myocardial infarction and stroke occurred in 122 (0.33%) and 126 (0.34%) patients, respectively, during the first 30 days after surgery. More patients with myocardial infarction had diabetes mellitus and cardiac disease (P = 0.041 and
ISSN:1538-7933
1538-7836
1538-7836
DOI:10.1111/j.1538-7836.2008.02948.x