Synthesis and biological evaluation of a series of 2′-fluorinated-2′,3′-dideoxy-2′,3′-didehydro-( l)-nucleosides

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1998-07, Vol.8 (13), p.1589-1594
Main Authors: Chen, Shu-Hui, Wang, Qin, Mao, John, King, Ivan, Dutschman, Ginger E., Gullen, Elizabeth A., Cheng, Yung-Chi, Doyle, Terrence W.
Format: Article
Language:English
Subjects:
AIDS/HIV
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral agents
Antiviral Agents - chemical synthesis
Antiviral Agents - chemistry
Antiviral Agents - pharmacology
Biological and medical sciences
Cell Line
Dideoxynucleosides - chemical synthesis
Dideoxynucleosides - chemistry
Dideoxynucleosides - pharmacology
Fluorine - chemistry
Hepatitis B virus - drug effects
HIV - drug effects
Humans
Medical sciences
Pharmacology. Drug treatments
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ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(98)00277-7