Verrucous carcinoma, then and now

The salient clinical and pathological features of verrucous carcinoma, as first described by Ackerman in 1948, are reviewed. Two case reports are presented. The first concerns a personal experience with a patient who had five surgical procedures for multifocal oral verrucous carcinoma and remains al...

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Bibliographic Details
Published in:The American journal of surgery 1998-11, Vol.176 (5), p.393-397
Main Author: Spiro, Ronald H.
Format: Article
Language:English
Subjects:
Biopsy
Cancer
Carcinoma, Verrucous - etiology
Carcinoma, Verrucous - history
Carcinoma, Verrucous - pathology
Carcinoma, Verrucous - surgery
Case reports
Cleveland G
Famous Persons
Female
Head and Neck Neoplasms - etiology
Head and Neck Neoplasms - history
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - surgery
History of medicine
History, 19th Century
Humans
Lymphatic system
Male
Metastasis
Middle Aged
Nitrous oxide
Oral cancer
Oral carcinoma
Palate
Patients
Plants, Toxic
Radiation
Surgery
Tobacco, Smokeless - adverse effects
Tumors
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Summary:The salient clinical and pathological features of verrucous carcinoma, as first described by Ackerman in 1948, are reviewed. Two case reports are presented. The first concerns a personal experience with a patient who had five surgical procedures for multifocal oral verrucous carcinoma and remains alive and well 28 years after her initial treatment. The second report highlights the remarkable story of President Grover Cleveland’s secret surgery for verrucous carcinoma of the palate in 1893. Current concepts about the management of this uncommon tumor are reviewed, as well as some recent investigations that deal with its etiology.
ISSN:0002-9610
1879-1883
DOI:10.1016/S0002-9610(98)00232-3