Chitosan: A Unique Polysaccharide for Drug Delivery

Abstract The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier. The first part of this review concerns the principal uses of chitosan as an excipient in oral formulations (particularly as a direct tableting agent) and as a vehi...

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Bibliographic Details
Published in:Drug development and industrial pharmacy 1998-01, Vol.24 (11), p.979-993
Main Authors: Felt, Olivia, Buri, Pierre, Gurny, Robert
Format: Article
Language:English
Subjects:
Administration, Oral
Animals
Biological and medical sciences
Chemistry, Pharmaceutical
Chitin - analogs & derivatives
Chitin - chemistry
Chitosan
Delayed-Action Preparations
Dosage Forms
Drug Carriers
Drug delivery
Drug Delivery Systems
Excipients
General pharmacology
Humans
Liposomes
Medical sciences
Microspheres
Pharmaceutical technology. Pharmaceutical industry
Pharmaceutical Vehicles
Pharmacology. Drug treatments
Review
Tablets
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Summary:Abstract The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier. The first part of this review concerns the principal uses of chitosan as an excipient in oral formulations (particularly as a direct tableting agent) and as a vehicle for parenteral drug delivery devices. The use of chitosan to manufacture sustained-release systems deliverable by other routes (nasal, ophthalmic, transdermal, and implantable devices) is discussed in the second part.
ISSN:0363-9045
1520-5762
DOI:10.3109/03639049809089942