Acute dermal abscesses caused by Serratia marcescens

Primary acute cutaneous infections caused by Serratia marcescens are extremely unusual. Nevertheless, Serratia infections are especially frequent in chronic granulomatous disease, which is a primary immunodeficiency that affects phagocytic cells of the innate immune system. We report a young man wit...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2008-05, Vol.58 (5), p.891-893
Main Authors: Soria, Xavier, MD, Bielsa, Isabel, PhD, Ribera, Miquel, PhD, Herrero, María José, PhD, Domingo, Helena, MD, Carrascosa, José Manuel, PhD, Ferrándiz, Carlos, PhD
Format: Article
Language:English
Subjects:
Abscess - drug therapy
Abscess - microbiology
Acute Disease
Adult
Biological and medical sciences
Ciprofloxacin - therapeutic use
Dermatology
Humans
Male
Medical sciences
Neutrophils - physiology
Serratia Infections - drug therapy
Serratia Infections - microbiology
Serratia marcescens - isolation & purification
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Summary:Primary acute cutaneous infections caused by Serratia marcescens are extremely unusual. Nevertheless, Serratia infections are especially frequent in chronic granulomatous disease, which is a primary immunodeficiency that affects phagocytic cells of the innate immune system. We report a young man without history of infections, who developed multiple dermal abscesses on a leg with chronic lymphoedema attributed to S marcescens . Laboratory investigations showed a delayed partial neutrophilic oxidative function. It is remarkable that the patient did not have any other infections during childhood, when most of the innate immune deficiencies are diagnosed, and he had no history of granulomatous lesions. We hypothesize that the delayed neutrophilic oxidative function could be explained by a partial neutrophilic oxidative function, which could be enough to maintain the patient asymptomatic until this infection.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2008.01.011