Helicobacter pylori serology in elderly people: a 21 -year cohort comparison in 70-year-olds and a 20-year longitudinal population study in 70–90-year-olds

Aims: (i) to compare Helicobacter pylori serology in two 70-year-old cohorts in Gothenburg, Sweden, born 21 years apart, (ii) to study H. pylori serology in a 70-year-old cohort over 20 years. Population and method: H. pylori serology at the age of 70 was investigated in 98 men and 132 women born in...

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Bibliographic Details
Published in:Age and ageing 1998-07, Vol.27 (4), p.433-436
Main Authors: Gause-Nilsson, Ingrid, Gnarpe, Håkan, Gnarpe, Judy, Lundborg, Per, Steen, Bertil
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Antibodies, Bacterial - analysis
Cohort Studies
Elderly people
Female
Gastrointestinal disorders
Helicobacter Infections - epidemiology
Helicobacter pylori
Helicobacter pylori - immunology
Humans
Longitudinal Studies
Male
Morbidity
population study
Relationship
Seroepidemiologic Studies
Socioeconomic conditions
Sweden
Sweden - epidemiology
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Summary:Aims: (i) to compare Helicobacter pylori serology in two 70-year-old cohorts in Gothenburg, Sweden, born 21 years apart, (ii) to study H. pylori serology in a 70-year-old cohort over 20 years. Population and method: H. pylori serology at the age of 70 was investigated in 98 men and 132 women born in 1901/02 and in 77 men and 113 women born in 1922. In 21 men and 40 women Helicobacter serology was monitored longitudinally with examinations at 70, 81, and 90 years of age. The analyses were performed on frozen samples by use of an in-house enzyme immunoassay with a sensitivity of 0.99, specificity of 1.00 and positive and negative predictive values of 0.96 and 1.00, respectively Absorbance values
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/27.4.433