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Benefits of Intrahospital Exercise Training after Pediatric Bone Marrow Transplantation

Abstract The purpose of this study was to determine if an eight-week intrahospital supervised, conditioning program improves functional capacity and quality of life (QOL) in children (4 boys, 4 girls) (mean [SD] age: 10.9 [2.8] years [range: 8 - 16]) who have undergone bone marrow transplantation (B...

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Bibliographic Details
Published in:International journal of sports medicine 2008-05, Vol.29 (5), p.439-446
Main Authors: San Juan, A. F., Chamorro-Viña, C., Moral, S., Fernández del Valle, M., Madero, L., Ramírez, M., Pérez, M., Lucia, A.
Format: Article
Language:English
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Summary:Abstract The purpose of this study was to determine if an eight-week intrahospital supervised, conditioning program improves functional capacity and quality of life (QOL) in children (4 boys, 4 girls) (mean [SD] age: 10.9 [2.8] years [range: 8 - 16]) who have undergone bone marrow transplantation (BMT) for leukemia treatment within the last 12 months. A group of 8 age and gender-matched healthy children served as controls. The experimental group performed 3 weekly sessions of resistance and aerobic training inside an intra-hospital gymnasium. A significant combined effect of group and time (p < 0.05) was observed for muscle functional capacity (Timed Up and Down Stairs [TUDS] test) and peak oxygen uptake (V·O 2peak ), i.e., with BMT children showing greater improvements than controls (V·O 2peak at pre- and post-training of 25.9 (8.2) and 31.1 (7.6) mL/kg/min in diseased children). Muscle strength (6 RM test for bench and leg press and seated row) also improved after training (p < 0.05) in the BMT group. Concerning QOL, a significant combined effect of group and time (p < 0.05) was also observed for children's self-report of comfort and resilience and for parents' report of their children's satisfaction and achievement. In summary, children who have received BMT experience physical and overall health benefits after a relatively short-term (8 weeks) supervised exercise training program.
ISSN:0172-4622
1439-3964
DOI:10.1055/s-2007-965571