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Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy
Background: Although pelvic exenteration is frequently indicated during surgery for gynaecological malignancy, performing a colorectal anastomosis remains contentious because of concern about leakage. This study evaluated the safety of performing a low colorectal anastomosis during pelvic exenterati...
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| Published in: | British journal of surgery 2008-06, Vol.95 (6), p.770-773 |
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| Main Authors: | , , , , , |
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| container_end_page | 773 |
| container_issue | 6 |
| container_start_page | 770 |
| container_title | British journal of surgery |
| container_volume | 95 |
| creator | Lim, S.-W. Lim, S.-B. Park, J.-Y. Park, S.-Y. Choi, H. S. Jeong, S.-Y. |
| description | Background:
Although pelvic exenteration is frequently indicated during surgery for gynaecological malignancy, performing a colorectal anastomosis remains contentious because of concern about leakage. This study evaluated the safety of performing a low colorectal anastomosis during pelvic exenteration for gynaecological malignancy.
Methods:
Between April 2001 and December 2006, 145 consecutive patients underwent low colorectal anastomosis without (122) or with (23) a stoma after pelvic exenteration for advanced primary or recurrent gynaecological malignancy. Subjects were assessed in terms of five patient‐, four disease‐ and two surgery‐related variables. The proportion of patients with each risk factor for leakage was found, and the rate of symptomatic anastomotic leakage was determined.
Results:
The mean age of the patients was 53·5 (range 10–77) years and the most common diagnosis was ovarian cancer (77·9 per cent). The mean operating time was 453 (range 145–845) min and the mean blood loss was 1080 (range 110–10 500) ml; 95 patients (65·5 per cent) required a blood transfusion. Of the 145 patients, 81 (55·9 per cent) had patient‐related, 94 (64·8 per cent) had disease‐related and 67 (46·2 per cent) had surgery‐related variables associated with a risk of leakage. Symptomatic anastomotic leakage developed in three patients (2·1 per cent).
Conclusion:
Although patients with gynaecological malignancy carry considerable risks associated with anastomotic leakage, carefully executed low colorectal anastomosis during pelvic exenteration was found to be safe. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Feasible despite risks |
| doi_str_mv | 10.1002/bjs.6135 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_69171779</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69171779</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3885-a9c5fe3f8b07a1a648cce5c0f45ed79d1feff389ba7ccb3e2434fba2d01c0c893</originalsourceid><addsrcrecordid>eNpF0U1v1DAQBmALUdGlIPELUC5wSzu2k9g5QgVtYdVKfEpwsCbOeOWSxFs7od1_T6Iu7WkOfmbkmZexVxyOOYA4aa7TccVl-YStuKzKXPBKP2UrAFA5l0IesucpXQNwCaV4xg65LrjWZb1iv6-m0YaeUhZcZkMXItkRuwwHTGPoQ5pf2in6YZNtqfvrbUZ3NIwUcfRhyFyI2WY3IC2tG2_nzh47vxlwsLsX7MBhl-jlvh6x7x8_fDs9z9dXZxen79a5lfMncqxt6Ug63YBCjlWhraXSgitKalXdckfOSV03qKxtJIlCFq5B0QK3YHUtj9jb-7nbGG4mSqPpfbLUdThQmJKpaq64Ugt8vYdT01NrttH3GHfm_zlm8GYPMM27uDiv4dODEyCFBiFnl9-7W9_R7nEOmCUOM8dhljjM-09fl_rofRrp7sFj_GMqJVVpfl6eGRDrX5_5lx9mLf8BgmKN9g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69171779</pqid></control><display><type>article</type><title>Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy</title><source>Oxford Journals Online</source><creator>Lim, S.-W. ; Lim, S.-B. ; Park, J.-Y. ; Park, S.-Y. ; Choi, H. S. ; Jeong, S.-Y.</creator><creatorcontrib>Lim, S.-W. ; Lim, S.-B. ; Park, J.-Y. ; Park, S.-Y. ; Choi, H. S. ; Jeong, S.-Y.</creatorcontrib><description>Background:
Although pelvic exenteration is frequently indicated during surgery for gynaecological malignancy, performing a colorectal anastomosis remains contentious because of concern about leakage. This study evaluated the safety of performing a low colorectal anastomosis during pelvic exenteration for gynaecological malignancy.
Methods:
Between April 2001 and December 2006, 145 consecutive patients underwent low colorectal anastomosis without (122) or with (23) a stoma after pelvic exenteration for advanced primary or recurrent gynaecological malignancy. Subjects were assessed in terms of five patient‐, four disease‐ and two surgery‐related variables. The proportion of patients with each risk factor for leakage was found, and the rate of symptomatic anastomotic leakage was determined.
Results:
The mean age of the patients was 53·5 (range 10–77) years and the most common diagnosis was ovarian cancer (77·9 per cent). The mean operating time was 453 (range 145–845) min and the mean blood loss was 1080 (range 110–10 500) ml; 95 patients (65·5 per cent) required a blood transfusion. Of the 145 patients, 81 (55·9 per cent) had patient‐related, 94 (64·8 per cent) had disease‐related and 67 (46·2 per cent) had surgery‐related variables associated with a risk of leakage. Symptomatic anastomotic leakage developed in three patients (2·1 per cent).
Conclusion:
Although patients with gynaecological malignancy carry considerable risks associated with anastomotic leakage, carefully executed low colorectal anastomosis during pelvic exenteration was found to be safe. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Feasible despite risks</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.6135</identifier><identifier>PMID: 18418859</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Adolescent ; Aged ; Anastomosis, Surgical ; Biological and medical sciences ; Blood Loss, Surgical ; Child ; Colon - surgery ; Female ; General aspects ; Genital Neoplasms, Female - surgery ; Humans ; Length of Stay ; Medical sciences ; Middle Aged ; Pelvic Exenteration - methods ; Rectum - surgery ; Risk Factors ; Surgical Wound Dehiscence - etiology ; Treatment Outcome</subject><ispartof>British journal of surgery, 2008-06, Vol.95 (6), p.770-773</ispartof><rights>Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><rights>2008 INIST-CNRS</rights><rights>2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3885-a9c5fe3f8b07a1a648cce5c0f45ed79d1feff389ba7ccb3e2434fba2d01c0c893</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20328023$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18418859$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lim, S.-W.</creatorcontrib><creatorcontrib>Lim, S.-B.</creatorcontrib><creatorcontrib>Park, J.-Y.</creatorcontrib><creatorcontrib>Park, S.-Y.</creatorcontrib><creatorcontrib>Choi, H. S.</creatorcontrib><creatorcontrib>Jeong, S.-Y.</creatorcontrib><title>Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
Although pelvic exenteration is frequently indicated during surgery for gynaecological malignancy, performing a colorectal anastomosis remains contentious because of concern about leakage. This study evaluated the safety of performing a low colorectal anastomosis during pelvic exenteration for gynaecological malignancy.
Methods:
Between April 2001 and December 2006, 145 consecutive patients underwent low colorectal anastomosis without (122) or with (23) a stoma after pelvic exenteration for advanced primary or recurrent gynaecological malignancy. Subjects were assessed in terms of five patient‐, four disease‐ and two surgery‐related variables. The proportion of patients with each risk factor for leakage was found, and the rate of symptomatic anastomotic leakage was determined.
Results:
The mean age of the patients was 53·5 (range 10–77) years and the most common diagnosis was ovarian cancer (77·9 per cent). The mean operating time was 453 (range 145–845) min and the mean blood loss was 1080 (range 110–10 500) ml; 95 patients (65·5 per cent) required a blood transfusion. Of the 145 patients, 81 (55·9 per cent) had patient‐related, 94 (64·8 per cent) had disease‐related and 67 (46·2 per cent) had surgery‐related variables associated with a risk of leakage. Symptomatic anastomotic leakage developed in three patients (2·1 per cent).
Conclusion:
Although patients with gynaecological malignancy carry considerable risks associated with anastomotic leakage, carefully executed low colorectal anastomosis during pelvic exenteration was found to be safe. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Feasible despite risks</description><subject>Adolescent</subject><subject>Aged</subject><subject>Anastomosis, Surgical</subject><subject>Biological and medical sciences</subject><subject>Blood Loss, Surgical</subject><subject>Child</subject><subject>Colon - surgery</subject><subject>Female</subject><subject>General aspects</subject><subject>Genital Neoplasms, Female - surgery</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pelvic Exenteration - methods</subject><subject>Rectum - surgery</subject><subject>Risk Factors</subject><subject>Surgical Wound Dehiscence - etiology</subject><subject>Treatment Outcome</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNpF0U1v1DAQBmALUdGlIPELUC5wSzu2k9g5QgVtYdVKfEpwsCbOeOWSxFs7od1_T6Iu7WkOfmbkmZexVxyOOYA4aa7TccVl-YStuKzKXPBKP2UrAFA5l0IesucpXQNwCaV4xg65LrjWZb1iv6-m0YaeUhZcZkMXItkRuwwHTGPoQ5pf2in6YZNtqfvrbUZ3NIwUcfRhyFyI2WY3IC2tG2_nzh47vxlwsLsX7MBhl-jlvh6x7x8_fDs9z9dXZxen79a5lfMncqxt6Ug63YBCjlWhraXSgitKalXdckfOSV03qKxtJIlCFq5B0QK3YHUtj9jb-7nbGG4mSqPpfbLUdThQmJKpaq64Ugt8vYdT01NrttH3GHfm_zlm8GYPMM27uDiv4dODEyCFBiFnl9-7W9_R7nEOmCUOM8dhljjM-09fl_rofRrp7sFj_GMqJVVpfl6eGRDrX5_5lx9mLf8BgmKN9g</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Lim, S.-W.</creator><creator>Lim, S.-B.</creator><creator>Park, J.-Y.</creator><creator>Park, S.-Y.</creator><creator>Choi, H. S.</creator><creator>Jeong, S.-Y.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200806</creationdate><title>Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy</title><author>Lim, S.-W. ; Lim, S.-B. ; Park, J.-Y. ; Park, S.-Y. ; Choi, H. S. ; Jeong, S.-Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3885-a9c5fe3f8b07a1a648cce5c0f45ed79d1feff389ba7ccb3e2434fba2d01c0c893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Aged</topic><topic>Anastomosis, Surgical</topic><topic>Biological and medical sciences</topic><topic>Blood Loss, Surgical</topic><topic>Child</topic><topic>Colon - surgery</topic><topic>Female</topic><topic>General aspects</topic><topic>Genital Neoplasms, Female - surgery</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pelvic Exenteration - methods</topic><topic>Rectum - surgery</topic><topic>Risk Factors</topic><topic>Surgical Wound Dehiscence - etiology</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lim, S.-W.</creatorcontrib><creatorcontrib>Lim, S.-B.</creatorcontrib><creatorcontrib>Park, J.-Y.</creatorcontrib><creatorcontrib>Park, S.-Y.</creatorcontrib><creatorcontrib>Choi, H. S.</creatorcontrib><creatorcontrib>Jeong, S.-Y.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lim, S.-W.</au><au>Lim, S.-B.</au><au>Park, J.-Y.</au><au>Park, S.-Y.</au><au>Choi, H. S.</au><au>Jeong, S.-Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2008-06</date><risdate>2008</risdate><volume>95</volume><issue>6</issue><spage>770</spage><epage>773</epage><pages>770-773</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
Although pelvic exenteration is frequently indicated during surgery for gynaecological malignancy, performing a colorectal anastomosis remains contentious because of concern about leakage. This study evaluated the safety of performing a low colorectal anastomosis during pelvic exenteration for gynaecological malignancy.
Methods:
Between April 2001 and December 2006, 145 consecutive patients underwent low colorectal anastomosis without (122) or with (23) a stoma after pelvic exenteration for advanced primary or recurrent gynaecological malignancy. Subjects were assessed in terms of five patient‐, four disease‐ and two surgery‐related variables. The proportion of patients with each risk factor for leakage was found, and the rate of symptomatic anastomotic leakage was determined.
Results:
The mean age of the patients was 53·5 (range 10–77) years and the most common diagnosis was ovarian cancer (77·9 per cent). The mean operating time was 453 (range 145–845) min and the mean blood loss was 1080 (range 110–10 500) ml; 95 patients (65·5 per cent) required a blood transfusion. Of the 145 patients, 81 (55·9 per cent) had patient‐related, 94 (64·8 per cent) had disease‐related and 67 (46·2 per cent) had surgery‐related variables associated with a risk of leakage. Symptomatic anastomotic leakage developed in three patients (2·1 per cent).
Conclusion:
Although patients with gynaecological malignancy carry considerable risks associated with anastomotic leakage, carefully executed low colorectal anastomosis during pelvic exenteration was found to be safe. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Feasible despite risks</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>18418859</pmid><doi>10.1002/bjs.6135</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of surgery, 2008-06, Vol.95 (6), p.770-773 |
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| language | eng |
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| source | Oxford Journals Online |
| subjects | Adolescent Aged Anastomosis, Surgical Biological and medical sciences Blood Loss, Surgical Child Colon - surgery Female General aspects Genital Neoplasms, Female - surgery Humans Length of Stay Medical sciences Middle Aged Pelvic Exenteration - methods Rectum - surgery Risk Factors Surgical Wound Dehiscence - etiology Treatment Outcome |
| title | Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy |
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