Loading…
RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder
We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects. RGS4 polymorp...
Saved in:
| Published in: | Neuroscience letters 2008-05, Vol.437 (1), p.25-28 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3 |
| container_end_page | 28 |
| container_issue | 1 |
| container_start_page | 25 |
| container_title | Neuroscience letters |
| container_volume | 437 |
| creator | Huuhka, Kaija Kampman, Olli Anttila, Sami Huuhka, Martti Rontu, Riikka Mattila, Kari M. Hurme, Mikko Lehtimäki, Terho Leinonen, Esa |
| description | We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects.
RGS4 polymorphism was not associated with treatment response in ECT or risk of MDD. According to the present data, the impact of
RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of
RGS4 polymorphism in treatment response in ECT. |
| doi_str_mv | 10.1016/j.neulet.2008.03.065 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69178294</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0304394008004114</els_id><sourcerecordid>21030277</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3</originalsourceid><addsrcrecordid>eNqFkU2LFDEQhoMo7rj6D0T6orduKx-ddC6CLOsqLAh-gLeQTqrZDN2dNukemH9vxhn0pqeCquctiqcIeUmhoUDl230z4zbi2jCArgHegGwfkR3tFKuVVuwx2QEHUXMt4Io8y3kPAC1txVNyRTvBBVC2Iz--3H0V1RLH4xTT8hDyVNnZVwnzEueM1RorHNGtKbo4H7Yxh0NpPmCyy7EKczXZfUyVx6Ukfs98yDF5TM_Jk8GOGV9c6jX5_uH2283H-v7z3aeb9_e1E4yuNQp7uhgEk61XkoOUvesplwDeO8-ltgMqJ7Rte1Rd32r0EoTGzvdO6oFfkzfnvUuKPzfMq5lCdjiOdsa4ZSM1VR3T4r8go0UXU6qA4gy6FHNOOJglhcmmo6FgTurN3pzVm5N6A9wU9SX26rJ_6yf0f0MX1wV4fQFsdnYckp1dyH84BpxK0XWFe3fmsGg7BEwmu4CzQx9S-YTxMfz7kl_giKUR</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>21030277</pqid></control><display><type>article</type><title>RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Huuhka, Kaija ; Kampman, Olli ; Anttila, Sami ; Huuhka, Martti ; Rontu, Riikka ; Mattila, Kari M. ; Hurme, Mikko ; Lehtimäki, Terho ; Leinonen, Esa</creator><creatorcontrib>Huuhka, Kaija ; Kampman, Olli ; Anttila, Sami ; Huuhka, Martti ; Rontu, Riikka ; Mattila, Kari M. ; Hurme, Mikko ; Lehtimäki, Terho ; Leinonen, Esa</creatorcontrib><description>We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects.
RGS4 polymorphism was not associated with treatment response in ECT or risk of MDD. According to the present data, the impact of
RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of
RGS4 polymorphism in treatment response in ECT.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/j.neulet.2008.03.065</identifier><identifier>PMID: 18434012</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>5' Untranslated Regions - genetics ; Adult ; Aged ; Aged, 80 and over ; Antidepressive Agents - therapeutic use ; Biological and medical sciences ; Depressive Disorder, Major - genetics ; Depressive Disorder, Major - therapy ; Drug Resistance ; Electroconvulsive Therapy ; Female ; Fundamental and applied biological sciences. Psychology ; Genotype ; Humans ; Major depression ; Male ; Middle Aged ; Polymorphism, Genetic - genetics ; Polymorphism, Single Nucleotide ; Psychiatric Status Rating Scales ; RGS Proteins - genetics ; RGS4 ; Vertebrates: nervous system and sense organs ; Young Adult</subject><ispartof>Neuroscience letters, 2008-05, Vol.437 (1), p.25-28</ispartof><rights>2008 Elsevier Ireland Ltd</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3</citedby><cites>FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20316488$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18434012$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huuhka, Kaija</creatorcontrib><creatorcontrib>Kampman, Olli</creatorcontrib><creatorcontrib>Anttila, Sami</creatorcontrib><creatorcontrib>Huuhka, Martti</creatorcontrib><creatorcontrib>Rontu, Riikka</creatorcontrib><creatorcontrib>Mattila, Kari M.</creatorcontrib><creatorcontrib>Hurme, Mikko</creatorcontrib><creatorcontrib>Lehtimäki, Terho</creatorcontrib><creatorcontrib>Leinonen, Esa</creatorcontrib><title>RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects.
RGS4 polymorphism was not associated with treatment response in ECT or risk of MDD. According to the present data, the impact of
RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of
RGS4 polymorphism in treatment response in ECT.</description><subject>5' Untranslated Regions - genetics</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Depressive Disorder, Major - genetics</subject><subject>Depressive Disorder, Major - therapy</subject><subject>Drug Resistance</subject><subject>Electroconvulsive Therapy</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genotype</subject><subject>Humans</subject><subject>Major depression</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Polymorphism, Genetic - genetics</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Psychiatric Status Rating Scales</subject><subject>RGS Proteins - genetics</subject><subject>RGS4</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Young Adult</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqFkU2LFDEQhoMo7rj6D0T6orduKx-ddC6CLOsqLAh-gLeQTqrZDN2dNukemH9vxhn0pqeCquctiqcIeUmhoUDl230z4zbi2jCArgHegGwfkR3tFKuVVuwx2QEHUXMt4Io8y3kPAC1txVNyRTvBBVC2Iz--3H0V1RLH4xTT8hDyVNnZVwnzEueM1RorHNGtKbo4H7Yxh0NpPmCyy7EKczXZfUyVx6Ukfs98yDF5TM_Jk8GOGV9c6jX5_uH2283H-v7z3aeb9_e1E4yuNQp7uhgEk61XkoOUvesplwDeO8-ltgMqJ7Rte1Rd32r0EoTGzvdO6oFfkzfnvUuKPzfMq5lCdjiOdsa4ZSM1VR3T4r8go0UXU6qA4gy6FHNOOJglhcmmo6FgTurN3pzVm5N6A9wU9SX26rJ_6yf0f0MX1wV4fQFsdnYckp1dyH84BpxK0XWFe3fmsGg7BEwmu4CzQx9S-YTxMfz7kl_giKUR</recordid><startdate>20080523</startdate><enddate>20080523</enddate><creator>Huuhka, Kaija</creator><creator>Kampman, Olli</creator><creator>Anttila, Sami</creator><creator>Huuhka, Martti</creator><creator>Rontu, Riikka</creator><creator>Mattila, Kari M.</creator><creator>Hurme, Mikko</creator><creator>Lehtimäki, Terho</creator><creator>Leinonen, Esa</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20080523</creationdate><title>RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder</title><author>Huuhka, Kaija ; Kampman, Olli ; Anttila, Sami ; Huuhka, Martti ; Rontu, Riikka ; Mattila, Kari M. ; Hurme, Mikko ; Lehtimäki, Terho ; Leinonen, Esa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>5' Untranslated Regions - genetics</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Depressive Disorder, Major - genetics</topic><topic>Depressive Disorder, Major - therapy</topic><topic>Drug Resistance</topic><topic>Electroconvulsive Therapy</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genotype</topic><topic>Humans</topic><topic>Major depression</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Polymorphism, Genetic - genetics</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Psychiatric Status Rating Scales</topic><topic>RGS Proteins - genetics</topic><topic>RGS4</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huuhka, Kaija</creatorcontrib><creatorcontrib>Kampman, Olli</creatorcontrib><creatorcontrib>Anttila, Sami</creatorcontrib><creatorcontrib>Huuhka, Martti</creatorcontrib><creatorcontrib>Rontu, Riikka</creatorcontrib><creatorcontrib>Mattila, Kari M.</creatorcontrib><creatorcontrib>Hurme, Mikko</creatorcontrib><creatorcontrib>Lehtimäki, Terho</creatorcontrib><creatorcontrib>Leinonen, Esa</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huuhka, Kaija</au><au>Kampman, Olli</au><au>Anttila, Sami</au><au>Huuhka, Martti</au><au>Rontu, Riikka</au><au>Mattila, Kari M.</au><au>Hurme, Mikko</au><au>Lehtimäki, Terho</au><au>Leinonen, Esa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>2008-05-23</date><risdate>2008</risdate><volume>437</volume><issue>1</issue><spage>25</spage><epage>28</epage><pages>25-28</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects.
RGS4 polymorphism was not associated with treatment response in ECT or risk of MDD. According to the present data, the impact of
RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of
RGS4 polymorphism in treatment response in ECT.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>18434012</pmid><doi>10.1016/j.neulet.2008.03.065</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 2008-05, Vol.437 (1), p.25-28 |
| issn | 0304-3940 1872-7972 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69178294 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | 5' Untranslated Regions - genetics Adult Aged Aged, 80 and over Antidepressive Agents - therapeutic use Biological and medical sciences Depressive Disorder, Major - genetics Depressive Disorder, Major - therapy Drug Resistance Electroconvulsive Therapy Female Fundamental and applied biological sciences. Psychology Genotype Humans Major depression Male Middle Aged Polymorphism, Genetic - genetics Polymorphism, Single Nucleotide Psychiatric Status Rating Scales RGS Proteins - genetics RGS4 Vertebrates: nervous system and sense organs Young Adult |
| title | RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T09%3A40%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=RGS4%20polymorphism%20and%20response%20to%20electroconvulsive%20therapy%20in%20major%20depressive%20disorder&rft.jtitle=Neuroscience%20letters&rft.au=Huuhka,%20Kaija&rft.date=2008-05-23&rft.volume=437&rft.issue=1&rft.spage=25&rft.epage=28&rft.pages=25-28&rft.issn=0304-3940&rft.eissn=1872-7972&rft.coden=NELED5&rft_id=info:doi/10.1016/j.neulet.2008.03.065&rft_dat=%3Cproquest_cross%3E21030277%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c421t-e4a187204265d763066bcb13600ddcd369afe7c49a5be78b59ed6049e8dbc69f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=21030277&rft_id=info:pmid/18434012&rfr_iscdi=true |