Vitamin D and blood pressure connection: update on epidemiologic, clinical, and mechanistic evidence

Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there...

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Bibliographic Details
Published in:Nutrition reviews 2008-05, Vol.66 (5), p.291-297
Main Authors: Martini, L.A, Wood, R.J
Format: Article
Language:English
Subjects:
angiotensin
Biological and medical sciences
blood pressure
Cardiovascular disease
cardiovascular diseases
cholecalciferol
chronic diseases
Dietary Supplements
Enzymes. Coenzymes. Vitamins. Pigments
Epidemiologic Studies
etiology
Evidence-Based Medicine
Fundamental and applied biological sciences. Psychology
human diseases
Humans
Hypertension
Hypertension - drug therapy
Hypertension - etiology
Kidney diseases
literature reviews
Medical research
Metabolisms and neurohumoral controls
Nutrition
nutritional status
public health
renin
Risk factors
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vitamin D
Vitamin D - physiology
Vitamin D - therapeutic use
Vitamin D Deficiency - complications
Vitamin D Deficiency - drug therapy
vitamin deficiencies
Vitamin deficiency
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Summary:Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there has been increasing interest concerning the role of vitamin D in chronic disease. The recent publication of several studies, highlighted in this brief review, supports an association between vitamin D status and blood pressure. It remains to be determined what level of vitamin D status needs to be achieved in different subpopulations to assure the maximum benefit of vitamin D status on blood pressure.
ISSN:0029-6643
1753-4887
DOI:10.1111/j.1753-4887.2008.00035.x