Outcome Analysis of Breast Cancer Patients Receiving Breast-Conserving Surgery in Southern Italy

The purpose of the current analysis was to evaluate the outcome of patients enrolled at the National Cancer Institute of Naples between 1997 and 2000, who underwent breast-conserving surgery. Between January 1997 and December 2000, 946 patients had been diagnosed with T1 or T2 (≤3 cm) breast carcino...

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Bibliographic Details
Published in:Journal of chemotherapy (Florence) 2008-04, Vol.20 (2), p.269-277
Main Authors: Frasci, G., Crispo, A., D'aiuto, G., Barba, M., Rinaldo, M., De Marco, M., Grimaldi, M., Capasso, I., Botti, G., Di Bonito, M., Montella, M.
Format: Article
Language:English
Subjects:
Adult
Aged
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Breast cancer
Breast Neoplasms - drug therapy
Breast Neoplasms - pathology
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
breast-conserving surgery
Combined Modality Therapy
Demography
Disease-Free Survival
Female
Gynecology. Andrology. Obstetrics
Humans
Italy
Lymph Nodes - pathology
Lymphatic Metastasis
Mammary gland diseases
Mastectomy, Segmental
Medical sciences
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local
Pharmacology. Drug treatments
Proportional Hazards Models
treatment
Treatment Outcome
Tumors
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Summary:The purpose of the current analysis was to evaluate the outcome of patients enrolled at the National Cancer Institute of Naples between 1997 and 2000, who underwent breast-conserving surgery. Between January 1997 and December 2000, 946 patients had been diagnosed with T1 or T2 (≤3 cm) breast carcinoma. At the time of the present analysis (31-12-2005), all patients had been followed for >5 years. A Cox proportional hazards model was performed. Overall, 7-year Locoregional Relapse-free survival (LRFS) and Distant Relapse-free Survival (DRFS) rates were 95.9% and 88.4%, respectively. Seven-year DRFS was 91.2% and 79.3% in T1 and T2 stage, respectively (p
ISSN:1120-009X
1973-9478
DOI:10.1179/joc.2008.20.2.269