Hypothalamic neuropeptide Y and plasma leptin after long-term high-fat feeding in the rat

The ingestion of fat by rodents affects the level of neuropeptide Y (NPY) in the hypothalamus and we hypothesized that they might be linked via leptin, the adipose tissue hormone. The influence of fat intake on leptin and NPY levels was studied in rats fed on either a high-fat (HF) or a low fat diet...

Full description

Saved in:
Bibliographic Details
Published in:Neuroscience letters 1998-10, Vol.254 (3), p.157-160
Main Authors: Stricker-Krongrad, A, Cumin, F, Burlet, C, Beck, B
Format: Article
Language:English
Subjects:
Adipose tissue
Adipose Tissue - physiology
Animals
Arcuate nucleus
Arcuate Nucleus of Hypothalamus - metabolism
Body weight
Diet, Fat-Restricted
Dietary Fats
Fat intake
Hypothalamus - metabolism
Insulin
Leptin
Male
Neuropeptide Y - metabolism
Ob protein
Paraventricular Hypothalamic Nucleus - metabolism
Paraventricular nucleus
Proteins - metabolism
Rats
Rats, Long-Evans
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The ingestion of fat by rodents affects the level of neuropeptide Y (NPY) in the hypothalamus and we hypothesized that they might be linked via leptin, the adipose tissue hormone. The influence of fat intake on leptin and NPY levels was studied in rats fed on either a high-fat (HF) or a low fat diet (LF) for 5 months. Ingestion of the HF diet increased fat deposition (+48%; P
ISSN:0304-3940
1872-7972
DOI:10.1016/S0304-3940(98)00678-8