Macular involvement in secondary systemic amyloidosis

A patient with subretinal and preretinal hemorrhage after secondary systemic amyloidosis due to familial Mediterranean fever is presented. Case presentation. A 30-year-old woman with secondary systemic amyloidosis secondary to familial Mediterranean fever presented with painless visual loss in the r...

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Bibliographic Details
Published in:European journal of ophthalmology 2008-05, Vol.18 (3), p.459-461
Main Authors: Altiparmak, U E, Koklu, B, Unlu, N, Yagci, R, Bayrak, R, Gul Yilmaz Cinar, F, Duman, S
Format: Article
Language:English
Subjects:
Adult
Amyloidosis - diagnosis
Amyloidosis - etiology
Amyloidosis - metabolism
Familial Mediterranean Fever - complications
Female
Fluorescein Angiography
Humans
Kidney Diseases - diagnosis
Kidney Diseases - etiology
Kidney Diseases - metabolism
Retinal Hemorrhage - diagnosis
Retinal Hemorrhage - etiology
Retinal Hemorrhage - metabolism
Serum Amyloid A Protein - metabolism
Tomography, Optical Coherence
Visual Acuity
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Summary:A patient with subretinal and preretinal hemorrhage after secondary systemic amyloidosis due to familial Mediterranean fever is presented. Case presentation. A 30-year-old woman with secondary systemic amyloidosis secondary to familial Mediterranean fever presented with painless visual loss in the right eye. The examination demonstrated multiple subretinal and preretinal hemorrhages, massive deposits which may represent amyloid material at the left macular region. After 6 months, the hemorrhages disappeared, but deposits persisted. The macular deposition and hemorrhage is an uncommon manifestation of secondary systemic amyloidosis secondary to familial Mediterranean fever. Further evidence is necessary to understand the nature of these deposits and their relevance to secondary systemic amyloidosis and/or familial Mediterranean fever.
ISSN:1120-6721
1724-6016
DOI:10.1177/112067210801800325