Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome

BACKGROUND: There is controversy regarding the application of transfusion triggers in cardiac surgery. The goal of this study was to determine if lowering the hemoglobin threshold for red cell (RBC) transfusion to 8 g per dL after coronary artery bypass graft surgery would reduce blood use without a...

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Bibliographic Details
Published in:Transfusion (Philadelphia, Pa.) Pa.), 1999-10, Vol.39 (10), p.1070-1077
Main Authors: Bracey, A.W., Radovancevic, R., Riggs, S.A., Houston, S., Cozart, H., Vaughn, W.K., Radovancevic, B., McAllister Jr, H.A., Cooley, D.A.
Format: Article
Language:English
Subjects:
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
CABG = coronary artery bypass grafting
Coronary Artery Bypass - mortality
CPB = cardiopulmonary bypass
Differential Threshold
Erythrocyte Transfusion
FACT-An = FACT-Anemia
FACT-F = Functional Assessment of Cancer Therapy-Fatigue
Female
Hb = hemoglobin
Health Surveys
Hemoglobins - analysis
Humans
ICU = intensive care unit
Length of Stay
Male
Medical sciences
Middle Aged
Morbidity
Postoperative Complications - epidemiology
RBC(s) = red cell(s)
Respiration, Artificial
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Surveys and Questionnaires
THI = Texas Heart Institute
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Treatment Outcome
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Summary:BACKGROUND: There is controversy regarding the application of transfusion triggers in cardiac surgery. The goal of this study was to determine if lowering the hemoglobin threshold for red cell (RBC) transfusion to 8 g per dL after coronary artery bypass graft surgery would reduce blood use without adversely affecting patient outcome. STUDY DESIGN AND METHODS: Consecutive patients (n = 428) undergoing elective primary coronary artery bypass graft surgery were randomly assigned to two groups: study patients (n = 212) received RBC transfusions in the postoperative period if the Hb level was
ISSN:0041-1132
1537-2995
DOI:10.1046/j.1537-2995.1999.39101070.x