TNF-α and chronic fatigue syndrome

Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results s...

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Bibliographic Details
Published in:Journal of clinical immunology 1999-09, Vol.19 (5), p.314-316
Main Authors: MOSS, R. B, MERCANDETTI, A, VOJDANI, A
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Cross-Sectional Studies
Fatigue Syndrome, Chronic - blood
Fatigue Syndrome, Chronic - immunology
Female
Humans
Male
Medical sciences
Middle Aged
Nervous system involvement in other diseases. Miscellaneous
Neurology
Retrospective Studies
Tumor Necrosis Factor-alpha - metabolism
Citations: Items that cite this one
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Summary:Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results suggest a significant increase serum TNF-alpha in patients with CFS (P
ISSN:0271-9142
1573-2592
DOI:10.1023/A:1020595709352