Development and application of endoloops for the treatment of bleeding esophageal varices

Background: Endoloops are detachable nylon snares. The aims of this study were to develop an endoscopic method for repeated delivery of endoloops to arrest variceal bleeding, to compare efficacy of endoloop hemostasis with injection and band ligation in experimental of endoloops in a pilot study in...

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Bibliographic Details
Published in:Gastrointestinal endoscopy 1999-11, Vol.50 (5), p.677-684
Main Authors: Hepworth, Clive C., Rodney Burnham, W., Paul Swain, C.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Diseases of the digestive system
Dogs
Equipment Design
Esophageal and Gastric Varices - surgery
Esophagoscopes
Gastrointestinal Hemorrhage - surgery
Hemostasis, Surgical - instrumentation
Hemostasis, Surgical - methods
Hemostasis, Surgical - statistics & numerical data
Humans
Ligation - instrumentation
Ligation - methods
Ligation - statistics & numerical data
Medical sciences
Nylons
Pilot Projects
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Random Allocation
Rubber
Statistics, Nonparametric
Stomach - surgery
Suction - instrumentation
Swine
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Summary:Background: Endoloops are detachable nylon snares. The aims of this study were to develop an endoscopic method for repeated delivery of endoloops to arrest variceal bleeding, to compare efficacy of endoloop hemostasis with injection and band ligation in experimental of endoloops in a pilot study in patients with varices. Methods: Technical modifications including ridged endcaps and alterations in angulation of endoloops were developed to speed delivery and improve efficacy. Hemostatic efficacy of endoloops was compared with sclerotherapy and band ligation in animal studies before studies in patients. Results: Modified endcap and endoloops allowed repeated applications without withdrawal of the endoscope. Right-angled endoloops ensnared more ( p
ISSN:0016-5107
1097-6779
DOI:10.1016/S0016-5107(99)80020-0