Similar effect of revascularization on technetium-99m sestamibi and 15-(p-iodophenyl)pentadecanoic acid uptake in myocardial infarction patients

To study its usefulness as a tracer for assessment of the perfusion and viability of myocardium, 15-(p-iodophenyl)pentadecanoic acid (IPPA) was compared with technetium-99m sestamibi (MIBI). Dual-tracer single-photon emission tomography rest imaging was performed no more than 2 months before and 3 m...

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Bibliographic Details
Published in:European journal of nuclear medicine 1999-10, Vol.26 (10), p.1304-1309
Main Authors: BENDEL, S, KETTUNEN, R, HARTIKAINEN, J, REMES, J, VANNINEN, E, JIWEI YANG, KUIKKA, J, HUIKURI, H
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Coronary Artery Bypass
Coronary heart disease
Echocardiography
Female
Heart
Humans
Iodobenzenes - pharmacokinetics
Male
Medical sciences
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - metabolism
Myocardial Infarction - surgery
Myocardial Revascularization
Myocardium - metabolism
Radiopharmaceuticals - pharmacokinetics
Technetium Tc 99m Sestamibi - pharmacokinetics
Tomography, Emission-Computed, Single-Photon
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Summary:To study its usefulness as a tracer for assessment of the perfusion and viability of myocardium, 15-(p-iodophenyl)pentadecanoic acid (IPPA) was compared with technetium-99m sestamibi (MIBI). Dual-tracer single-photon emission tomography rest imaging was performed no more than 2 months before and 3 months after coronary artery bypass grafting in 28 patients with previous anterior (n=13) or inferior (n=15) infarction. The size of MIBI and IPPA defects decreased from 14%+/-12% and 13%+/-9% to 10%+/-11% and 9%+/-7%, respectively (P
ISSN:0340-6997
1619-7070
1619-7089
DOI:10.1007/s002590050587