Computer-aided detection of pulmonary embolism: Influence on radiologists’ detection performance with respect to vessel segments

The purpose was to assess the sensitivity of a CAD software prototype for the detection of pulmonary embolism in MDCT chest examinations with regard to vessel level and to assess the influence on radiologists’ detection performance. Forty-three patients with suspected PE were included in this retros...

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Bibliographic Details
Published in:European radiology 2008-07, Vol.18 (7), p.1350-1355
Main Authors: Das, Marco, Mühlenbruch, Georg, Helm, Anita, Bakai, Annemarie, Salganicoff, Marcos, Stanzel, Sven, Liang, Jianming, Wolf, Matthias, Günther, Rolf W., Wildberger, Joachim Ernst
Format: Article
Language:English
Subjects:
Chest
Clinical Competence
Contrast Media
Diagnostic Radiology
Embolism
Female
Humans
Imaging
Internal Medicine
Interventional Radiology
Iodine
Iohexol - analogs & derivatives
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Patients
Prototypes
Pulmonary Embolism - diagnostic imaging
Pulmonary embolisms
Radiographic Image Interpretation, Computer-Assisted
Radiology
Sensitivity analysis
Sensitivity and Specificity
Software
Tomography
Tomography, X-Ray Computed - methods
Ultrasound
Vessels
Work stations
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Summary:The purpose was to assess the sensitivity of a CAD software prototype for the detection of pulmonary embolism in MDCT chest examinations with regard to vessel level and to assess the influence on radiologists’ detection performance. Forty-three patients with suspected PE were included in this retrospective study. MDCT chest examinations with a standard PE protocol were acquired at a 16-slice MDCT. All patient data were read by three radiologists (R1, R2, R3), and all thrombi were marked. A CAD prototype software was applied to all datasets, and each finding of the software was analyzed with regard to vessel level. The standard of reference was assessed in a consensus read. Sensitivity for the radiologists and CAD software was assessed. Thirty-three patients were positive for PE, with a total of 215 thrombi. The mean overall sensitivity for the CAD software alone was 83% (specificity, 80%). Radiologist sensitivity was 77% = R3, 82% = R2, and R1 = 87%. With the aid of the CAD software, sensitivities increased to 98% (R1), 93% (R2), and 92% (R3) (p
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-008-0889-x