Idiopathic calcinosis cutis presenting as labial lesions in children: Report of two cases with literature review

Calcinosis cutis is a general term for calcium deposition in the skin. It may be due to abnormal calcium or phosphorus metabolism, damage to the dermal collagen, or idiopathic. It has been found in the skin of many areas of the body, including the face, extremities, penis, scrotum and mons pubis. We...

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Bibliographic Details
Published in:Journal of pediatric & adolescent gynecology 1999-08, Vol.12 (3), p.157-160
Main Authors: Bernardo, B.D., Huettner, P.C., Merritt, D.F., Ratts, V.S.
Format: Article
Language:English
Subjects:
Calcinosis - diagnosis
Calcinosis - pathology
Calcinosis cutis
Child
Child Abuse, Sexual - diagnosis
Diagnosis, Differential
Female
Humans
Labial lesions
Vulva
Vulva - pathology
Vulvar Diseases - diagnosis
Vulvar Diseases - pathology
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Summary:Calcinosis cutis is a general term for calcium deposition in the skin. It may be due to abnormal calcium or phosphorus metabolism, damage to the dermal collagen, or idiopathic. It has been found in the skin of many areas of the body, including the face, extremities, penis, scrotum and mons pubis. We report two cases of calcinosis cutis presenting as lesions of the labia majora in children. A 6 1/2-year-old girl presented with labial lesions of unknown etiology. There was no history of sexual abuse or trauma. Excisional biopsy was performed and histopathological evaluation showed subepithelial calcification. Follow-up laboratory evaluation revealed normal serum calcium and phosphorus levels. Screening tests for collagen vascular diseases were negative. An 8-year-old girl presented for evaluation of a “labial cyst”. The lesion was first noted 6 months prior to presentation and had not resolved, despite treatment with topical creams and sitz baths. Excisional biopsy was performed and histopathological evaluation showed multiple nodules of calcified and amorphous debris surrounded by histiocytes and giant cells. We report two cases of idiopathic calcinosis cutis presenting as labial lesions in children. Because it can be mistaken for a sexually transmitted disease, recognition and proper diagnosis of this condition is essential. Additionally, work-up to rule out abnormalities of phosphorus or calcium metabolism and collagen vascular diseases may be indicated.
ISSN:1083-3188
1873-4332
DOI:10.1016/S1038-3188(99)00010-8